People often oppose the implementation of flood mitigation measures based on concerns about “spatial quality” (SQ). SQ can be an ambiguous concept, which function as boundary object that unites stakeholders from various backgrounds. Yet, ambiguity also misused to justify particular interests, result in unmet expectations and lead miscommunication. To contribute understanding, communication risk...

A number of murine models are used to mimic the pathology of breast cancer. Tissue inoculation and cell inoculation using orthotopic implantation (OS) and subcutaneous implantation (SQ) are commonly used to generate murine models to investigate cancer. However, limited information is available in regard to the variations of these methods. The present study compared growth, metastasis, survival ...

BACKGROUND/AIMS Poor sleep quality (SQ) is associated with increased cardiovascular mortality and morbidity. Additionally, asymmetric dimethylarginine (ADMA) is an independent predictor of cardiovascular mortality and morbidity. However, no sufficient data regarding the relationship between ADMA levels and SQ have been reported. The goal of the current study was to evaluate the association betw...

OBJECTIVES/HYPOTHESIS Nasal obstruction is a cardinal symptom in diagnosing chronic rhinosinusitis (CRS), and decreased sleep quality (SQ) and quality of life (QOL) are commonly reported in CRS. It is, however, unclear what role nasal obstruction severity plays in this decreased SQ and QOL. Using validated instruments, we evaluated the relationship between nasal obstruction severity, SQ, and QO...

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin cancer worldwide. Despite improvement in therapeutic strategies, the prognosis of advanced HNSCC remains poor. The extacellular lipid mediators known as lysophosphatidic acids (LPAs) have been implicated in tumorigenesis of HNSCC. LPAs activate G-protein-coupled receptors not only in the endothelial differentiation ...

ADRIAN STURZA1,2#, LAVINIA NOVEANU1,2#, OANA DUICU1,2 MARIA DANILA1,2, NORBERT JOST1,2, DANINA MUNTEAN1,2*, MIRCEA MUNTEANU3 1“Victor Babes University of Medicine and Pharmacy, Faculty of Medicine, Department of Pathophysiology, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania 2 “Victor Babes University of Medicine and Pharmacy, Center for Translational Research and Systems Medicine, 2 Eftimie M...

Let Q be a finite set of points in the plane. For any set P of points in the plane, SQ(P ) denotes the number of similar copies of Q contained in P . For a fixed n, Erdős and Purdy asked to determine the maximum possible value of SQ(P ), denoted by SQ(n), over all sets P of n points in the plane. We consider this problem when Q = △ is the set of vertices of an isosceles right triangle. We give ...

In order to study the effectiveness of the mg/sq m, BCNU. 75 mg/sq m. and prednidrug combination BCNU. cyclophosphasone, 80 mg/sq m, for 7 days, every 4 wk. mide, and prednisone (BCP) in myeloma. and were evaluated for response after 6 the Southeastern Cancer Study Group mo of therapy. Responding patients were entered 1 26 previously untreated and 33 continued on therapy and followed for ovalpr...

BACKGROUND Abnormal execution of several movements in a sequence is a frequent finding in schizophrenia. Successful performance of such motor acts requires correct integration of cortico-subcortical processes, particularly those related to cerebellar functions. Abnormal connectivity between cortical and cerebellar regions with resulting cognitive dysmetria has been proposed as the core dysfunct...

The Southeastern Cancer Study Group conducted a post-remission induction randomized trial in adult acute myelogenous leukemia to assess the efficacy of alternate drug therapy during consolidation and of immunotherapy during maintenance. Of 508 evaluable patients entered into the study, 335 (66%) achieved a complete remission treated with a 7-day infusion of cytosine arabinoside at a dose of 100...