The percentage removal of phenol from aqueous solution by emulsion liquid membrane and emulsion leakage was investigated experimentally for various parameters such as membrane: internal phase ratio, membrane: external phase ratio, emulsification speed, emulsification time, carrier concentration, surfactant concentration and internal agent concentration. These parameters strongly influence the p...

Recent studies have shown that it should be possible to control lipid bioavailability through food structural approaches. Nevertheless, the gastrointestinal-tract physiological conditions must also be considered. To get a better understanding of this phenomenon, we evaluated the effect of emulsification, as well as the use of sodium caseinate or chitosan, on the postprandial bioavailability of ...

Objective: This study aimed to increase the effectiveness of using zeaxanthin by developed nanoemulsion containing which was then formulated into radiance serum for topical use.
 Methods: Nanoemulsions are made spontaneous nano emulsification methods/techniques, relatively simple technologically because they rely on right combination selected surfactants and co-surfactants. The optimizatio...

preparation of tretinoin-containing microspheres with the aim of reducing undesirable skin reactions towards trans retinoic acid (tra) and thus, improving patient compliance is of particular interest. these microspheres have to be smaller than 30 m m to avoid causing gritty feel when applying on the skin, and slow the release of drug to minimize its skin side effects. following preliminary eval...

The aim of this investigation was to design and develop nanoemulsions (NEs) as novel ophthalmic delivery systems for brinzolamide (BZD). Phase behavior of quaternary systems composed of triacetin and CapryolTM 90 (selected oils, screened through the solubility studies), various surfactants (namely, Cremophor RH 40, Brij 35, Labrasol and tyloxapol), Transcutol P (as co-surfactant) an...

The polymeric nanoparticles are prepared from biocompatible polymers in size between 10-1000 nm. Chitosan is a biocompatible polymer that - can be utilized as drug delivery systems. In this study, chitosan nanoparticles were synthesized using an optimized spontaneous emulsification method. Determining particle size and morphology are two critical parameters in nanotechnology. The aim of this st...

Abstract Background Pemigatinib is a small molecule tyrosine kinase inhibitor of fibroblast growth factor receptor inhibitors. The oral bioavailability constricted due to its limited solubility at physiological pH. It essential develop novel formulation improve the intrinsic and reduce pharmacokinetic variability. Self-nanoemulsifying drug delivery system an effective, smart more adequate appro...