نتایج جستجو برای: spoligotyping

تعداد نتایج: 649  

Journal: :Journal of clinical microbiology 2007
E M Streicher T C Victor G van der Spuy C Sola N Rastogi P D van Helden R M Warren

Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity i...

Journal: :Journal of clinical microbiology 2008
Ewa Augustynowicz-Kopec Tomasz Jagielski Zofia Zwolska

The genetic compositions of 71 isoniazid-resistant Mycobacterium tuberculosis strains from Poland were determined by spoligotyping. Nearly 80% of the isolates belonged to either the T or the Haarlem family. The genotypic diversity was largely due to variation within those families. The scarcity of imported genotypes suggested that the M. tuberculosis population studied has an endemic nature.

2006
Neil E. Jenkins Mike B.J. Beadsworth James J. Anson Fred J. Nye Vanessa J. Martlew Nick J. Beeching

We describe a severely immunosuppressed HIV-1-positive man in whom immune restoration disease associated with pulmonary infection caused by Mycobacterium microti developed after antiretroviral treatment. The diagnosis was made by using convenient spoligotyping techniques, but invasive investigations were required to exclude a tumor.

Journal: :Journal of clinical microbiology 2005
Bouke C de Jong Anthony Onipede Alex S Pym Sebastien Gagneux Roxanne S Aga Kathryn DeRiemer Peter M Small

Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.

2015
Kangjam Rekha Devi Rinchenla Bhutia Shovonlal Bhowmick Kaustab Mukherjee Jagadish Mahanta Kanwar Narain Igor Mokrousov

Tuberculosis (TB) is one of the major public health concerns in Assam, a remote state located in the northeastern (NE) region of India. The present study was undertaken to explore the circulating genotypes of Mycobacterium tuberculosis complex (MTBC) in this region. A total of 189 MTBC strains were collected from smear positive pulmonary tuberculosis cases from different designated microscopy c...

2014
Adama Sanou Zekiba Tarnagda Estelle Kanyala Dezemon Zingué Moumini Nouctara Zakaria Ganamé Adjima Combary Hervé Hien Mathurin Dembele Antoinette Kabore Nicolas Meda Philippe Van de Perre Dorine Neveu Anne Laure Bañuls Sylvain Godreuil Joseph M. Vinetz

BACKGROUND In sub-Saharan Africa, bovine tuberculosis (bTB) is a potential hazard for animals and humans health. The goal of this study was to improve our understanding of bTB epidemiology in Burkina Faso and especially Mycobacterium bovis transmission within and between the bovine and human populations. METHODOLOGY/PRINCIPAL FINDINGS Twenty six M. bovis strains were isolated from 101 cattle ...

2014
Yi Liu Miao Tian Xueke Wang Rongrong Wei Qing Xing Tizhuang Ma Xiaoying Jiang Wensheng Li Zhiguo Zhang Yu Xue Xuxia Zhang Wei Wang Tao Wang Feng Hong Junjie Zhang Sumin Wang Chuanyou Li Jonathan Hon-Kwan Chen

BACKGROUND Tuberculosis (TB) is a serious problem in China. While there have been some studies on the nationwide genotyping of Mycobacterium tuberculosis (M. tuberculosis), there has been little detailed research in Beijing, the capital of China, which has a huge population. Here, M. tuberculosis clinical strains collected in Beijing during 2009 were genotyped by classical methods. METHODOLOG...

2017
Minako Hijikata Naoto Keicho Le Van Duc Shinji Maeda Nguyen Thi Le Hang Ikumi Matsushita Seiya Kato

BACKGROUND Spacer oligonucleotide typing (spoligotyping), a widely used, classical genotyping method for Mycobacterium tuberculosis complex (MTBC), is a PCR-based dot-blot hybridization technique to detect the genetic diversity of the direct repeat (DR) region. Of the seven major MTBC lineages in the world, lineage 1 (Indo-Oceanic) mostly corresponds to the East African-Indian (EAI) spoligotype...

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