UNLABELLED (123)I-FP-CIT ((123)I-N-omega-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenyl)nortropane) is a SPECT dopamine transporter (DAT) tracer that probes dopaminergic cell loss in Parkinson's disease (PD). Quantification of (123)I-FP-CIT images is performed at equilibrium using a ratio (BR) of specific (striatal) to nonspecific (occipital) uptake with values obtained from regions of int...

The self-protecting multipath (SPM) is a simple and efficient endto-end protection switching mechanism for transport networks. It distributes the traffic of a demand between two nodes according to a specific load balancing function over several disjoint paths and redistributes it if one of them fails. The load balancing functions can be optimized so that backup capacity in the network is optima...

In contrast to animals, where polyamine (PA) catabolism efficiently converts spermine (Spm) to putrescine (Put), plants have been considered to possess a PA catabolic pathway producing 1,3-diaminopropane, Delta(1)-pyrroline, the corresponding aldehyde, and hydrogen peroxide but unable to back-convert Spm to Put. Arabidopsis (Arabidopsis thaliana) genome contains at least five putative PA oxidas...

The local brain function has been traditionally investigated based on the correlation of dysfunction with sites of brain lesions. The investigation of relationships between brain function and brain anatomy in both normal subjects and cooperative patients is now a reality through the advent of noninvasive brain monitoring techniques such as positron emission tomography using 15O-water and functi...

Brain imaging data have so far revealed a wealth of information about neuronal circuits involved in higher mental functions like memory, attention, emotion, language etc. Our efforts are toward understanding the learning related effects in brain activity during the acquisition of visuo-motor sequential skills. The aim of this paper is to survey various methods and approaches of analysis that al...

OBJECTIVE To investigate the pattern of perfusion abnormalities in ictal and interictal brain perfusion SPECT images (BSI) from patients with temporal lobe epilepsy (TLE). METHOD It was acquired interictal and ictal BSI from 24 patients with refractory TLE. BSIs were analyzed by visual inspection and statistical parametric mapping (SPM2). Statistical analysis compared the patients group to a ...

In the present study, the spermine (SPM) analogue N1N12-bis(ethyl)spermine (BESPM) is compared with SPM in its ability to regulate ornithine decarboxylase (ODC) and S-adenosyl-L-methionine decarboxylase (AdoMetDC) activities in intact L1210 cells and in the mechanism(s) by which this is accomplished. Unlike the comparable spermidine (SPD) analogue N1N8-bis(ethyl)spermidine, which regulates only...

Glutathione S-transferases (GST) detoxify carcinogens in tobacco smoke, which plays a major role in development of not only squamous cell carcinoma of the head and neck (SCCHN) but also second primary malignancy (SPM) after index SCCHN. We hypothesized that GSTM1 null, GSTT1 null, GSTP1 Ile(105)Val, and GSTP1 Ala(114)Val polymorphisms would individually and, more likely, collectively show an as...