Abstract Background Grey platelet syndrome (GPS) is a rare cause of mild-to-severe bleeding. Up till now, there has been no definite treatment for GPS. Case presentation We reported case diagnosed as GPS and presented with menorrhagia, metrorrhagia, gingival bleeding, left hypochondrial pain. The count was 18 thousand/cmm. Ultrasound splenic diameter 22.0 cm. multidisciplinary team decided to p...

We have previously shown that ANP causes differential constriction of the splenic vasculature of the rat (veins greater than arteries), which may be inhibited by blocking the production of cGMP with A7195. In this paper, we report experiments done on vessels derived from guanylyl cyclase (GC)-A knockout mice. Small splenic arteries ( approximately 150-microm diameter) and veins ( approximately ...

RATIONALE Splenic artery aneurysm (SAA) is the most common visceral artery aneurysm, while most SAAs are treated by endovascular or open procedures. PATIENT CONCERNS Here we present a case of SAA treated by laparoscopic aneurysmectomy with end-to-end anastomosis. DIAGNOSES A 40-year-old woman was incidentally found to have an asymptomatic distal SAA. CT scan revealed the SAA to be located a...

Pharmacological characteristics of the canine isolated splenic artery were investigated by the cannula insertion method for observing vascular responses to vasoactive agents and periarterial nerve stimulation. Four alpha-adrenoceptor agonists and tyramine induced vasoconstrictions in a dose-dependent manner, and the order of potency was noradrenaline (NA) > phenylephrine > clonidine > methoxami...

Giant splenic artery aneurysm is a rare condition that represents an eminent life threatening for the patient, requiring, therefore, urgent surgical correction. A 61-year-old woman, former smoker, hypertensive, hypercholesterolemic and multipara sought our service because of a large tumor in the mesogastrium, which was an abdominal ultrasound finding. Despite the size of the tumor, the patient ...

with an incidence of 0.01 –0.20 % in routine autopsies [1]. They occur most commonly in the splenic artery (60%) [2]. Left gastric artery aneurysms are extremely rare [3]. Multiple aneurysms are present in approximately a third of patients [4]. Here we describe a case with aneurysms arising from the left gastric and splenic arteries, presenting with massive upper gastrointestinal bleeding. A 73...

The spleen has been recently reported as one of the unusual extrapulmonary organs that can be affected by COVID-19. Different splenic lesions were described in COVID-19 patients. Herein, we summarize a few recent reports have association with Splenic infarction was frequently, ruptured and abscess also reported. involvement COVID -19 caused through direct virus damage and/or induced microvascul...

Splenic artery aneurysms occur infrequently in the normal population, but presents with increased incidence among cirrhotic patients with portal hypertension. The optimal management of splenic artery aneurysms and the prevention of spontaneous rupture in these patients present a therapeutic challenge for transplant physicians and surgeons. We discuss a case of SAA rupture in a liver transplant ...

Splenic artery aneurysm rupture is rare and potentially fatal. It has largely been reported in pregnant patients and typically not diagnosed until laparotomy. This case reports a constellation of clinical and sonographic findings that may lead clinicians to rapidly diagnose ruptured splenic artery aneurysm at the bedside. We also propose a rapid, but systematic sonographic approach to patients ...

Tuberculosis involving the pancreas is rare. We report a patient with pancreatic tuberculosis complicated by haemorrhage from a splenic artery pseudoaneurysm. As far as we are aware, the development of a splenic artery pseudoaneurysm in association with a large caseating mass of tuberculous pancreatic lymph nodes has not been reported previously. We review the literature and discuss the varied ...