background: a lot of remedies, mostly plant based, were mentioned in the persian old pharmacopoeias for promoting of burn and wound healing and tissue repairing. the efficacy of most of these old remedies is unexplored till now. adiantum capillus‑veneris from adiantaceae family is one of them that was used to treating of some kinds of chronic wounds. methods: methanol extract was fractionated t...

Here, we present a low-cost method to produce compact arrays using microporous materials and reagent jetting. Oligonucleotides are immobilized on membrane sheets as a series of lines. The membrane sheet is then rolled and bound, and the spiral structure is cut like a "jelly roll" to produce identical arrays. The spiral arrays behave much like larger formats using membranes, and hybridization de...

When single cells or tissues are injured, the wound must be repaired quickly in order to prevent cell death, loss of tissue integrity, and invasion by microorganisms. We describe Drosophila as a genetically tractable model to dissect the mechanisms of single-cell wound repair. By analyzing the expression and the effects of perturbations of actin, myosin, microtubules, E-cadherin, and the plasma...

Background: Burns are among the most common traumas in developing countries, which consume large amounts of medical resources. It is important to find an appropriate material for dressing of burn wounds that improves healing and is readily available, easily applicable, and economical. Methods: In a single-blind randomized controlled clinical trial from March to October 2006, 211 patients with l...

We present a new method for estimating the corotation radius in tightly wound spiral galaxies, through analysis of the radial variation of the offset between arms traced by the potential (P-arms) and those traced by dust (D-arms). We have verified the predictions of semi-analytical theory through hydrodynamical simulations and have examined the uniqueness of the galactic parameters that can be ...

OBJECTIVE To determine the distribution of alpha1, alpha3, and alpha5 chains of type IV collagen in the cochlea in Alport syndrome. DESIGN Case-control study. PATIENTS Two patients with sensorineural hearing loss due to Alport syndrome. Both patients had known mutations in the COL4A5 gene. MAIN OUTCOME MEASURES Immunostaining was used to study the distribution of type IV collagen (alpha1,...

introduction: it is believed that injury potential has a regulatory role in wound healing process and the application of exogenous electrical stimulation may serve to mimic the natural endogenous bioelectric current so that can improve the wound healing. up to now, this hypothesis has not been researched in surgically acute wounds. materials and methods: thirty nine male guinea pigs were random...

the past decade has witnessed the revival of amniotic membrane transplantation (amt) in ophthalmology. the importance of amt is due to its ability to reduce scarring and inflammation and to enhance wound healing and epithelialization, and also its anti-microbial properties. amniotic membrane has recently been used as a substrate for culturing limbal stem cells for transplantation. it has been u...

We hypothesized that the requirement for Ca(2+)-dependent exocytosis in cell-membrane repair is to provide an adequate lowering of membrane tension to permit membrane resealing. We used laser tweezers to form membrane tethers and measured the force of those tethers to estimate the membrane tension of Swiss 3T3 fibroblasts after membrane disruption and during resealing. These measurements show t...

This review provides a comprehensive overview on the quickly developing field of polymeric hollow fiber (HF) nanofiltration (NF), including membrane (module) and process design, operational parameters, full-scale applications. Six different methods are currently used to produce HF NF membranes: phase inversion, interfacial polymerization, grafting, coating, polyelectrolyte multilayers (PEM) che...