spink1

Dong Gao Ian Vela Andrea Sboner Phillip J. Iaquinta Wouter R. Karthaus Anuradha Gopalan Catherine Dowling Jackline N. Wanjala Eva A. Undvall Vivek K. Arora John Wongvipat Myriam Kossai Sinan Ramazanoglu Luendreo P. Barboza Wei Di Zhen Cao Qi Fan Zhang Inna Sirota Leili Ran Theresa Y. MacDonald Himisha Beltran Juan-Miguel Mosquera Karim A. Touijer Peter T. Scardino Vincent P. Laudone Kristen R. Curtis Dana E. Rathkopf Michael J. Morris Daniel C. Danila Susan F. Slovin Stephen B. Solomon James A. Eastham Ping Chi Brett Carver Mark A. Rubin Howard I. Scher Hans Clevers Charles L. Sawyers Yu Chen

The lack of in vitro prostate cancer models that recapitulate the diversity of human prostate cancer has hampered progress in understanding disease pathogenesis and therapy response. Using a 3D organoid system, we report success in long-term culture of prostate cancer from biopsy specimens and circulating tumor cells. The first seven fully characterized organoid lines recapitulate the molecular...

متن کامل

Relapsing pancreatitis due to a novel compound heterozygosity in the CFTR gene involving the second most common mutation in central and eastern Europe [CFTRdele2,3(21 kb)].

Journal: :Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2005

Georg Lamprecht Ulrike A Mau Christian Kortum Armin Raible Martin Stern Olaf Riess Michael Gregor

A 43-year-old otherwise healthy female patient presented with mild pancreatitis. Her family history revealed that her only son had cystic fibrosis. Genotyping of the patient demonstrated CFTR compound heterozygosity CFTRdele2,3(21 kb) and R117H and wild type alleles of the poly-T-tract in intron 8 (7T/7T). No mutations were detected in the cationic pancreatic trypsinogen (PRSS1) and the pancrea...

متن کامل

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

Co-existence of CFTR and SPINK1 Gene Mutations in an Idiopathic Chronic Pancreatitis Case

Integrated traditional Chinese medicine improves acute pancreatitis via the downregulation of PRSS1 and SPINK1

SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer

Detection of a large genomic deletion in the pancreatic secretory trypsin inhibitor (SPINK1) gene

SPINK1 Is a Susceptibility Gene for Fibrocalculous Pancreatic Diabetes in Subjects from the Indian Subcontinent

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

Relapsing pancreatitis due to a novel compound heterozygosity in the CFTR gene involving the second most common mutation in central and eastern Europe [CFTRdele2,3(21 kb)].

Prognostic value of ERG, PTEN, CRISP3 and SPINK1 in predicting biochemical recurrence in prostate cancer

Association of SPINK1 Expression and TMPRSS2:ERG Fusion with Prognosis in Endocrine-Treated Prostate Cancer

Epigenetic silencing of miRNA-338-5p and miRNA-421 drives SPINK1-positive prostate cancer