BACKGROUND Spinal cord injuries result in critical pecuniary and/or non-pecuniary losses due to the developing neurological problems. The objective of this study was to evaluate spinal injuries in terms of clinical severity and prognosis. Spinal injuries lead to serious clinical results due to the high rates of morbidity and mortality; however, there is a lack of reliable information on spinal ...

This study reviews the literature concerning possible therapeutic approaches for spinal cord injury. Spinal cord injury is a disabling and irreversible condition that has high economic and social costs. There are both primary and secondary mechanisms of damage to the spinal cord. The primary lesion is the mechanical injury itself. The secondary lesion results from one or more biochemical and ce...

Spinal cord injury is devastating injury, which has serious impact not only to the individual but also to family members, society and the nations as a whole because the available treatment options are expensive, prolong, resource consuming and do not always fulfill the expectation of patient and family members. Worldwide incidence of spinal cord injury has been reported up to 236-1009/million/y...

a neurological disorder is any disorder of the nervous system is usually due to cell loss. the ultimate goal of cns therapy is to replace lost cells and tissue. there is no neuroprotective, pharmacological and effective treatment available that restores the injury-induced loss of function. recent studies suggest that identification of adult neural stem/progenitor cells indwelling in the neuroge...

many experimental studies have reported behavioral improvement after transplantation of peripheral nerve tissue into the contused spinal cord, even in large animals. the safety of this treatment in human remains unknown. in this translational phase 1 study, safety of peripheral nerve grafting for chronic spinal cord injuries and possible outcomes are being reported. twelve complete motor spinal...

BACKGROUND Spinal cord injury (SCI) is recognised to cause hypotension and bradycardia (neurogenic shock). Previous studies have shown that the incidence of this in the emergency department (ED) may be low. However these studies are relatively small and have included a mix of blunt and penetrating injuries with measurements taken over different time frames. The aim was to use a large database t...

The highly debilitating nature of spinal cord injuries has provided much inspiration for the design of novel biomaterials that can stimulate cellular regeneration and functional recovery. Many experts agree that the greatest hope for treatment of spinal cord injuries will involve a combinatorial approach that integrates biomaterial scaffolds, cell transplantation, and molecule delivery. This ma...

The magnetic splint and complementary adapted objects allow patients with high-level spinal cord injuries independence in retrieving commonly used objects. This device has proved effective for patients with high-level spinal cord injuries who are not presently using an assistive splint and who are capable of bringing the hand to the mouth, often with the assistance of a mobile arm support or ov...

Citation: Sköld MK and Fehlings MG (2017) Editorial: Karolinska Institutet 200-Year Anniversary Symposium on Injuries to the Spinal Cord and Peripheral Nervous System—An Update on Recent Advances in Regenerative Neuroscience. Front. Neurol. 8:510. doi: 10.3389/fneur.2017.00510 Editorial: Karolinska institutet 200-Year anniversary Symposium on injuries to the Spinal Cord and Peripheral Nervous S...