BACKGROUND Many studies have shown that regional anesthesia improves postoperative outcome and particularly lessens infection by attenuating perioperative immunosuppression related to the stress response to surgery and general anesthesia. However, it remains to be determined whether regional anesthesia improves oncologic outcome after surgery. METHODS C57BL/6 mice were subjected to laparotomy...

BACKGROUND It was aimed to compare the efficacy and adverse effects of levobupivacaine alone and in combination with fentanyl and sufentanil during transurethral resection of the prostate (TURP) under spinal anesthesia. MATERIALS AND METHODS In this prospective, randomized, double-blind trial, 60 patients undergoing elective TURP under spinal anesthesia were randomized into three groups. Ten ...

BACKGROUND Adequate analgesia following caesarean section decreases morbidity, hastens ambulation, improves patient outcome and facilitates care of the newborn. Intrathecal magnesium, an NMDA antagonist, has been shown to prolong analgesia without significant side effects in healthy parturients. We therefore studied the effect of adding intrathecal magnesium sulphate to bupivacaine-fentanyl spi...

Single spinal anesthesia in transurethral resection of bladder tumor (TURBT) has been reported to be unable to prevent obturator nerve stimulation and adductor muscle contraction, which can cause complications like bladder perforation. The present study aimed to compare the effectiveness of the classic and inguinal approaches for obturator nerve block (ONB). Seventy patients with cancers of the...

OBJECTIVE This study was designed to evaluate analgesia (pain intensity and analgesic consumption) and the time of discharge of patients who underwent ilioinguinal (II) and iliohypogastric (IH) nerve block associated with wound infiltration with 0.75% ropivacaine, or not, after inguinal hernia repair surgery under spinal anesthesia. METHODS This was a prospective, randomized, double-blind stu...

Recent case reports suggest there may be an increased risk of abnormally high blockade ("high spinal") from subarachnoid anesthesia if it is performed immediately after epidural anesthesia. We describe two cases of high spinal anesthesia following failed epidural block in obstetric patients scheduled for cesarean delivery. Using a retrospective chart review, we estimate the incidence of high sp...

BACKGROUND: Post-dural puncture headache is a symptom often found in post-operative patients who receive spinal anesthesia. Therefore, therapy to reduce patient complaints becomes comparison find the best alternative for action. This case discusses post-dural risk factors post-cesarean section and sphenopalatine ganglion block as an pain intervention. CASE PRESENTATION: The 26-year-old woman, G...

     The overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. Acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. It would be of particular importance to interrupt the progress of events h...

Postdural puncture headache (PDPH) is a significant complication of spinal anesthesia. There is considerable variability in the incidence of PDPH, which is affected by a number of factors including age, gender, pregnancy, and needle type and size. We present a case where a patient had PDPH after a spinal block with a deformed spinal needle due to calcified interspinous ligaments. We suggest, in...