Three cases of recurrent generalized muscle spasms were reported. All three cases are of Chinese descent and show some typical features of recurrent painful muscle cramps, alopecia, diarrhea and abnormalities of bone and endocrine systems. Recurrent generalized muscle spasms or Satoyoshi's disease is recognized as an entity of the disease not only in Japan but also in China. The result that one...

The clinical features, differential diagnosis and treatment of unilateral spasms of the jaw and masticatory muscles are discussed and illustrated by eight cases of unilateral jaw spasms of various aetiologies. These include focal dystonia of the jaw, hemimasticatory spasm with and without facial hemiatrophy, paroxysmal events in multiple sclerosis and tetany. Attention is particularly drawn to ...

OBJECTIVE To compare the effectiveness of 2 novel antiepileptic drugs, topiramate and levetiracetam, as a second line treatment for infantile spasm when oral steroids fail. METHODS Forty infants under 2 years with clinically- and EEG-proven infantile spasms that did not respond to prednisone (2mg/kg/day in 2 divided doses) were recruited and randomized into 2 groups. They were randomly assign...

1 Polysynaptic excitatory postsynaptic potentials that trigger spasms 2 after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. 3 4 Katherine C. Murray, Marilee J. Stephens, Michelle Rank, Jessica D’Amico, 5 Monica A. Gorassini and David J. Bennett 6 Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada 7 8 9 Running Title: 5-HT1 receptors inhibit spas...