1 MSc in Oral Pathology. PhD Student Graduate program in oral pathology Federal University of Rio Grande do Norte. 2 MSc in Oral Pathology. PhD Student Graduate program in oral pathology Federal University of Rio Grande do Norte. 3 PhD in oral Pathology. Adjunct Professor Graduate program in oral pathology Federal University of Rio Grande do Norte. Universidade Federal do Rio Grande do Norte Se...

In recent years, there has been a growing interest in exploring the application of single-photon avalanche diode (SPAD) optical wireless communication (OWC). As photon counting detector, SPAD can provide much higher sensitivity compared to other commonly used photodetectors. However, SPAD-based receivers suffer from significant dead-time-induced non-linear distortion and signal dependent noise....

Single-photon avalanche diodes (SPADs) are widely used for weak light detection due to their high gain and sensitivity. Unfortunately, SPAD devices have random telegraph signal (RTS) noise during the transition phase, which makes circuit design more difficult. Therefore, modeling of RTS in is great significance processing circuits. However, not included traditional equivalent model. In response...

We analyze the global pharmaceutical industry network using a unique database that covers strategic transactions (i.e. alliance, financing and acquisition collaborations) for the top 90 global pharmaceutical firms and their ego-network partnerships totaling 4735 members during 1991-2012. The network evolution is traced via a novel method based on the concept of dynamicity that quantifies indivi...

A new imager for 3D near-infrared imaging has been designed based on a single-photon avalanche diode (SPAD) imager with 128x128 pixels capable of performing time-resolved measurements with a resolution of 97ps. The imager linearity has been improved to make more accurate measurements. A new optical setup has been implemented in order to prove the suitability of this kind of sensors for this app...

This work presents a dual-junction, single-photon avalanche diode (SPAD) with electrical μ-lens designed and simulated in 90 nm standard complementary metal oxide semiconductor (CMOS) technology. The evaluated structure can collect the photons impinging beneath the pixel guard ring, as well as the pixel active area. The fill factor of the SPAD increases from 12.5% to 42% in comparison with simi...

Sickle-cell intrahepatic cholestasis (SCIC) is an uncommon complication of sickle-cell disease (SCD), which can be life-threating if left untreated. We present the case of a 28-year-old man with SCD, who presented with jaundice and abdominal pain, one month after hydroxyurea discontinuation. Laboratory investigation revealed solely increased serum bilirubin, mainly conjugated, and imaging studi...

Whole-cell biosensors are potential candidates for on-line and in situ environmental monitoring. In this work we present a new design of a whole-cell bioluminescence biosensor for water toxicity detection, based on genetically engineered Escherichia coli bacteria, carrying a recA::luxCDABE promoter-reporter fusion. Sensitive optical detection is achieved using a single photon avalanche photodio...

Photon counting detectors such as single-photon avalanche diode (SPAD) arrays can be employed to achieve reliable optical wireless communication at power limited regimes. However, SPAD-based receivers suffer from significant dead-time induced intersymbol interference (ISI) especially when the incident photon rate is relatively high and dead time comparable or even larger than symbol duration, i...