نتایج جستجو برای: soy isoflavone

تعداد نتایج: 10758  

Journal: :Menopause 2011
H. Utian

OBJECTIVES If and to what extent soy protein, soy isoflavones, and their metabolites, including S(--)-equol, have beneficial effects on women's health is currently unclear. The North American Menopause Society (NAMS)/Utian Translational Science Symposium on Soy and Soy Isoflavones convened October 9-10, 2010, to clarify basic and clinical research findings as they relate to the risk and benefit...

Journal: :Cancer prevention research 2012
Seema A Khan Robert T Chatterton Nancy Michel Michelle Bryk Oukseub Lee David Ivancic Richard Heinz Carola M Zalles Irene B Helenowski Borko D Jovanovic Adrian A Franke Maarten C Bosland Jun Wang Nora M Hansen Kevin P Bethke Alexander Dew Margerie Coomes Raymond C Bergan

Soy isoflavone consumption may protect against breast cancer development. We conducted a phase IIB trial of soy isoflavone supplementation to examine its effect on breast epithelial proliferation and other biomarkers in the healthy high-risk breast. One hundred and twenty-six consented women underwent a random fine-needle aspiration (rFNA); those with 4,000 or more epithelial cells were randomi...

Journal: :Journal of Agricultural and Food Chemistry 2002

2012
S. Bolca M. Bracke H. Depypere

In developed countries, the life expectancy of women is currently extending more than 30 years beyond the age of menopause. The menopausal transition is often associated with complaints. The conflicting results on the effectivity of phytoestrogens to alleviate menopausal symptoms. This discrepancy in treatment effect may be due to the large interindividual variation in isoflavone bioavailabilit...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000
X Xu A M Duncan K E Wangen M S Kurzer

Isoflavones are soy phytoestrogens that have been suggested to be anticarcinogenic. Our previous study in premenopausal women suggested that the mechanisms by which isoflavones exert cancer-preventive effects may involve modulation of estrogen metabolism away from production of potentially carcinogenic metabolites [16alpha-(OH) estrone, 4-(OH) estrone, and 4-(OH) estradiol] (X. Xu et al., Cance...

2010
Gertraud Maskarinec Martijn Verheus Jeffrey A. Tice

Isoflavones, phytoestrogens in soy beans with estrogen-like properties, have been examined for their cancer protective effects. Mammographic density is a strong predictor of breast cancer. This review summarizes studies that have examined the association between isoflavones and breast density. Observational investigations in Hawaii and Singapore suggest slightly lower breast density among women...

Journal: :Nutrition and cancer 2002
Mi-Ae Yi Hyun M Son Jung-Soon Lee Chong-Suk Kwon Jin Kyu Lim Young Keun Yeo Young Sik Park Jong-Sang Kim

Several studies have suggested that soybean intake is associated with a lower risk of prostate cancer. However, the mechanism of prostate cancer prevention by soybeans remains unclear. Because prostate cancer is reported to have an association with an increased level of dihydrotestosterone (DHT) and soybean isoflavones are known to inhibit 5 alpha-reductase, which is involved in the conversion ...

Journal: :Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 2014
Mohammad H Javanbakht Reza Sadria Mahmoud Djalali Hoda Derakhshanian Payam Hosseinzadeh Mahnaz Zarei Gholamreza Azizi Reza Sedaghat Abbas Mirshafiey

BACKGROUND AND OBJECTIVES Nephrotic syndrome is a chronic disease especially common in the childhood and adolescence. Reactive oxygen species (ROS) and free radicals have significant role in the pathogenesis of nephrotic syndrome. The aim of this study was to evaluate the effect of soy protein and genistein (main isoflavone of soybean) on renal antioxidant status of nephrotic rats. METHODS Th...

Journal: :Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016
Mathias Schmidt Karin Arjomand-Wölkart Martin H Birkhäuser Andrea R Genazzani Doris M Gruber J Huber Heinz Kölbl Samo Kreft Sepp Leodolter Doris Linsberger Markus Metka Tommaso Simoncini Lucija Vrabic Dezman

The association between an increased uptake of isoflavones and a reduced frequency of menopausal hot flushes was first described in 1992, based on a lower incidence of hot flushes in countries with a high consumption of soy. Since then, numerous clinical trials with various sources of isoflavones including soy and red clover have been presented, with practically all of the studies with adequate...

2016
Jun Yamada Shozo Jinno

Throughout life, production of new neurons (granule cells) continues in the hippocampus of mammals including humans. Adult-generated granule cells play an important role in regulation of hippocampus-dependent cognitive functions and emotional behavior [1]. Each process of adult hippocampal neurogenesis is controlled by a variety of extrinsic and intrinsic factors. For instance, physical restrai...

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