نتایج جستجو برای: sox3

تعداد نتایج: 228  

Journal: :Neuron 2003
Victoria Graham Jane Khudyakov Pamela Ellis Larysa Pevny

Neural progenitors of the vertebrate CNS are defined by generic cellular characteristics, including their pseudoepithelial morphology and their ability to divide and differentiate. SOXB1 transcription factors, including the three closely related genes Sox1, Sox2, and Sox3, universally mark neural progenitor and stem cells throughout the vertebrate CNS. We show here that constitutive expression ...

Journal: :Mechanisms of Development 2002
Isaac Skromne Claudio D. Stern

In the chick embryo, two secreted factors have recently be shown to cooperate in inducing the first axial structure, the primitive streak: cWnt8C (normally expressed around the circumference of the embryo, in the marginal zone) and the TGF beta superfamily member cVg1 (expressed in the posterior part of the marginal zone) (Development 128 (2001) 2915). Misexpression of Vg1 in the anterior margi...

2018
Lu Wang Daniel Hiler Beisi Xu Issam AlDiri Xiang Chen Xin Zhou Lyra Griffiths Marc Valentine Abbas Shirinifard András Sablauer Suresh Thiagarajan Marie-Elizabeth Barabas Jiakun Zhang Dianna Johnson Sharon Frase Michael A. Dyer

Diverse cell types can be reprogrammed into pluripotent stem cells by ectopic expression of Oct4 (Pou5f1), Klf4, Sox3, and Myc. Many of these induced pluripotent stem cells (iPSCs) retain memory, in terms of DNA methylation and histone modifications (epigenetic memory), of their cellular origins, and this may bias subsequent differentiation. Neurons are difficult to reprogram, and there has not...

Journal: :The Journal of Cell Biology 2006
Sander H. Diks Robert J. Bink Sandra van de Water Jos Joore Carina van Rooijen Fons J. Verbeek Jeroen den Hertog Maikel P. Peppelenbosch Danica Zivkovic

From a differential display designed to isolate genes that are down-regulated upon differentiation of the central nervous system in Danio rerio embryos, we isolated d-asb11 (ankyrin repeat and suppressor of cytokine signaling box-containing protein 11). Knockdown of the d-Asb11 protein altered the expression of neural precursor genes sox2 and sox3 and resulted in an initial relative increase in...

Journal: :Frontiers in Marine Science 2022

The reproductive-related studies, including genetic and genomic such as gonadal transcriptome analyses, have previously focused on the adult spotted scat, with little information juvenile fish. Transcriptomics is a powerful tool that allows for massive parallel analysis to identify differential expression patterns of gene holistically at particular stage in cell or tissue development. This stud...

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