Alzheimer’s disease (AD) is the major cause of dementia in elderly population. Neuropathological features of AD are the extracellular plaques and intracellular neurofibrillary tangles (NFTs). Plaques are composed of amyloid-β (Aβ) peptide and NFTs contain hyperphosphorylated tau protein [1]. Genetic and biochemical studies suggest that extracellular Aβ deposition triggers pathological events le...
