Castleman’s disease is an uncommon disease with poorly understood etiopathogenesis. It was described by Benjamin Castleman in 1954. It commonly occurs in the mediastinal nodes. Virtually any lymphnodal area can be affected. Extranodal involvement is rare and occurs in the lung, pancreas, breast, adrenals, and muscle. Castleman’s disease rarely occurs in the pelvic cavity and only 18 such cases ...

SUMMARY The function of serum in the composition of culture media for trypano-somes was investigated with Trypanosoma cruxi. Serum supplies stearic acid, essential for the growth of this trypanosome. A liquid heat-steriliz-able medium, composed of peptone and known chemicals is described. The growth of T. cruxi in this medium reached 70 x lo8 trypanosomes/ml.

In their recent paper in Cell, Furuyama and Henikoff (2009) report that nucleosomes in centromeres may be right-handed, that is, they wrap DNA in a right-handed manner and induce positive supercoils. This raises intriguing new questions, such as how centromeric histone variants may be assembled into right-handed particles, and why chromatin would retain negative supercoiling in chromosome arms ...

It has been demonstrated that solid hepatoma lysosomes lack hyaluronidase activity, whereas normal rat liver lyso somes contain a high level of this enzyme. This result was also found with lysosomes from an ascites hepatoma, Walker carcinoma 256, and virally transformed BHK cells. In contrast, 0-yV-acetylglucosaminidase activity was shown to be present in lysosomes from tumor cells, although it...

tandem metacentric compound X chromosome is composed of two X chromoA somes attached to a medially located centromere and arranged in tandem sequence so that the synaptic configuration is a spiral (NOVITSKI 1954). An approximation to the tandem metacentric has been achieved by the construction of an attached-X heterozygous for Zn(l)y4 ( SIDOROV, SOKOLOV and TROFIMOV 1936; STURTEVANT and BEADLE ...

MARCHESANI (1939) first described the syndrome which is named after him, and since the appearance of his report cases have been described in European and American literature. The characteristic features of this syndrome are: (1) Brachycephaly, small stature, short limbs, brachydactyly, short squat fingers and toes with broad hands and feet, limitation of movement at the joints, and well-develop...

Broad ligament pregnancy also termed as interligamentous pregnancy is a rare form of ectopic pregnancy. Incidence is reported as 1 in 300 ectopic pregnancies. A broad ligament pregnancy usually results from trophoblastic penetration of tubal pregnancy through the tubal serosa and into the mesosalpinx, with secondary implantation between the leaves of broad ligament. It can also occur if a uteri...

In 1937 Bietti reported a tapetoretinal degeneration with associated corneal deposits at the limbus. The hallmark of the disease was the crystalline characteristics of the retinal spots as well as those at the corneal limbus. Bagolini and Ioli-Spade in 1968 presented a 30 year follow-up on Bietti's cases and presented six additional cases. The present report delas with this entity in Orientals,...