نتایج جستجو برای: soluble st2

تعداد نتایج: 90441  

2016
Nuria Alonso Josep Lupón Jaume Barallat Marta de Antonio Mar Domingo Elisabet Zamora Pedro Moliner Amparo Galán Javier Santesmases Cruz Pastor Dídac Mauricio Antoni Bayes-Genis

BACKGROUND Patients with diabetes mellitus (DM) have an increased risk of developing heart failure (HF). Further, DM is associated with poor prognosis in patients with HF. Our aim was to determine whether DM has any impact on the predictive value of a multi-biomarker panel in patients with HF. METHODS We included 1069 consecutive ambulatory HF patients in the study: age 66.2 ± 12.8 years, 33....

Journal: :Acta Microbiologica et Immunologica Hungarica 2015

Journal: :Cancer research 2014
Anaïs Levescot Stéphane Flamant Sara Basbous Florence Jacomet Olivier Féraud Elvire Anne Bourgeois Marie-Laure Bonnet Christine Giraud Lydia Roy Anne Barra Jean-Claude Chomel Ali Turhan François Guilhot Jean-Philippe Girard Jean-Marc Gombert André Herbelin

Although it is generally acknowledged that cytokines regulate normal hematopoiesis in an autocrine/paracrine fashion, their possible role in chronic myelogenous leukemia (CML) and resistance to imatinib mesylate treatment remain poorly investigated. Here, we report that CD34(+) progenitors from patients with CML at diagnosis are selectively targeted by the cytokine/alarmin interleukin (IL)-33. ...

Journal: :Journal of immunology 2010
Jinghua Liu Julliette M Buckley H Paul Redmond Jiang Huai Wang

Activation of TLR signaling is critical for host innate immunity against bacterial infection. Previous studies reported that the ST2 receptor, a member of the Toll/IL-1 receptor superfamily, functions as a negative regulator of TLR4 signaling and maintains LPS tolerance. However, it is undetermined whether ST2 negatively regulates TLR2 signaling and furthermore, whether a TLR2 agonist, bacteria...

Journal: :Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2016
Cinta Llibre Elisabet Zamora Àngel Caballero Josep Lupón Alba Ros Nuria Benito Marta de Antonio Amparo Galán Mar Domingo Antoni Bayes-Genis

CONTEXT Prognostic value of ST2 levels and dynamics has not been investigated in acute heart failure (AHF) using prospective real-life measurements. OBJECTIVE The objective of this study is to investigate the prognostic value of ST2 in AHF. METHODS ST2 levels were determined at admission (n = 182) and discharge (n = 85). Primary endpoint was the composite of all-cause death and HF rehospita...

Journal: :RFC 1998
Muneyoshi Suzuki

Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Abstract This document specifies an ATM-based protocol for communication between ST2+ agents. The ST2+ over ATM protocol supports the matching of one hop in an ST2+ tree-structure stream with one ATM connection. In this docu...

Journal: :JACC. Heart failure 2015
Antonio Lax Jesus Sanchez-Mas Maria C Asensio-Lopez Maria J Fernandez-Del Palacio Luis Caballero Iris P Garrido Francisco J Pastor-Perez James L Januzzi Domingo A Pascual-Figal

OBJECTIVES This study aimed to evaluate the specific role of the 2 available mineralocorticoid receptor antagonists (MRAs), eplerenone and spironolactone, on the modulation of galectin-3 (Gal-3) and interleukin (IL)-33/ST2 signaling in an experimental model of left ventricular systolic dysfunction after acute myocardial infarction (MI). BACKGROUND The molecular mechanisms of benefits of MRAs ...

2017
Kenji Tago Satoshi Ohta Megumi Funakoshi‐Tago Chihiro Aoki‐Ohmura Jitsuhiro Matsugi Shin‐ichi Tominaga Ken Yanagisawa

The ST2 gene was originally identified as a primary responsive gene induced by stimulation with growth factors and by oncogenic stress. The ST2 gene harbors two distinct promoters - a distal promoter and a proximal promoter. In this study, we identified a novel type of serum-responsive element in the ST2 proximal promoter using reporter gene analysis; this element includes a possible responsive...

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