A method for determining the concentration of iodide in beer using high-performance liquid chromatography/electrochemical detection was developed. Simple sample pretreatment of beer was performed using a monolithic silica disk-packed spin column, with a recovery rate of 84.9%. Separation of iodide ions from other endogenous compounds was carried out using a mobile phase of 10 mM sodium phosphat...

I . Iodine metabolism was studied using labelled sodium iodide in subjects with endemic goitre which is prevalent in the south-west part of Ceylon, where the iodine content of the drinking water was shown to be low. The study was confined mostly to children of school age. 2. The patients showed raised thyroidal uptake of lS1I and 48 h serum protein-bound radioactive iodine, lowered plasma inorg...

UNLABELLED Pertechnetate (as (99m)TcO(4)(-)), (123)I(-), and (131)I(-) have a long and successful history of use in the diagnosis and therapy of thyroid cancer, with uptake into thyroid tissue mediated by the sodium-iodide symporter (NIS). NIS has also emerged as a potential target for radiotherapy of nonthyroid malignancies that express the endogenous or transfected symporter. Perrhenates (as ...

The purpose of this study was to document the accuracy of (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) with sodium iodide detectors in characterizing indeterminate lung nodules or masses and in identifying additional extra-lesional findings. 50 consecutive patients without a confident diagnosis of malignancy on CT underwent (18)FDG PET with and without attenuation cor...

UNLABELLED 131I therapy is a widely accepted treatment for metastatic differentiated thyroid cancer. To investigate the feasibility of 131I therapy for breast cancer, we established breast cancer cells stably expressing Na-/I- symporter (NIS) gene that can be modulated and studied in vitro and in vivo. METHODS We transfected rat NIS genes into a human breast cancer cell line (MCF7) by electro...