Abstract Carboxymethyl cellulose(CMC) was extracted from cultivated banana peel (BP) agricultural waste. Cellulose first BP through delignification, bleaching and hydrolysis processes. Then, CMC prepared by the carboxymethylation reaction using monochloroacetic acid as a modifying agent. A mixture of 30% sodium hydroxide solution isopropanol used solvent medium for etherification with time 1-5 ...

We have used atomistic simulations to study the role of electrostatic screening and charge correlation effects in self-assembly processes of ionic surfactants into micelles. Specifically, we employed grand canonical Monte Carlo simulations to investigate the critical micelle concentration (cmc), aggregation number, and micellar shape in the presence of explicit sodium chloride (NaCl). The two s...

To facilitate the development of bio-based chemicals from renewable and inexpensive natural resources, we sought to produce biosurfactants using non-edible jatropha oil. Twenty yeasts known to produce biosurfactants were tested in this study, and Stamerella bombicola NBRC 10243 was found to use jatropha oil efficiently to produce sophorolipids (SLs) as a mixture of lactone-form SL (L-SL) and ac...

With the aim of directly predicting the functionality and mechanism of disintegrants during the disintegration and dissolution of tablets, we investigated an analysis method based on available surface area, which is the surface area of a drug in a formulation in direct contact with the external solvent during dissolution. We evaluated the following disintegrants in this study: sodium starch gly...

Some excipients are currently available for the formulation of Pharmaceutical suspensions. The purpose of this study is to search for a cheap and effective natural excipient that can be used as an effective alternative for the formulation of pharmaceutical suspensions. The mucilage from the pods of Abelmoschus esculentus was subjected to preformulation study for evaluation of its safety and sui...

Pineapple leaf waste, with its high cellulose content, can serve as alternative starting material for the production of carboxymethyl (CMC). In this study, synthesis conditions CMC from pineapple leaves via use microwave heating were optimized. Box-Behnken design and response surface methodology applied to schedule experiments optimize condition, respectively. Preparation was investigated by va...

The purpose of this study is to obtain information that can be used to improve controlled release and residence time of drugs on the liver surface. Using carboxymethylcellulose sodium salt (CMC-Na) and polyvinyl alcohol (PVA), we examined the effect of viscous formulations on the absorption of phenol red as a model. In the presence of 3% CMC-Na or 15% PVA, the maximum plasma concentration of ph...