نتایج جستجو برای: smooth muscle tumors

تعداد نتایج: 565347  

Journal: :Neoplasia 2011
Andreas Birbach David Eisenbarth Nicolas Kozakowski Eva Ladenhauf Marc Schmidt-Supprian Johannes A Schmid

In prostate cancers, epidemiological data suggest a link between prostate inflammation and subsequent cancer development, but proof for this concept in a tumor model is lacking. A constitutively active version of IκB kinase 2 (IKK2), which is activated by many inflammatory stimuli, was expressed specifically in the prostate epithelium. Constitutive activation of the IKK2/nuclear factor κB axis ...

Journal: :Ceskoslovenska patologie 2006
M Zámecník M Staník

So-called dedifferentiation in mesenchymal neoplasms of the uterus is very rare. Among conventional low-grade stromal tumors only three cases of dedifferentiation were reported, whereas in mixed stromal-smooth muscle tumors the dedifferentiation was yet not described. Here we present such a case of low-grade mixed stromal-smooth muscle tumor with dedifferentiation. The tumor occurred in 52-year...

2017
Justine L. Pickett Angela Chou Juliana A. Andrici Adele Clarkson Loretta Sioson Amy Sheen Jessica Reagh Fedaa Najdawi Yoomee Kim Denise Riley Jayne Maidens David Nevell Kirsten McIlroy Susan Valmadre Greg Gard Russell Hogg John Turchini Gregory Robertson Michael Friedlander Anthony J. Gill

Inflammatory myofibroblastic tumor (IMT) of the female genital tract is under-recognized. We investigated the prevalence of ALK-positive IMT in lesions previously diagnosed as gynecologic smooth muscle tumors. Immunohistochemistry (IHC) for ALK was performed on tissue microarrays of unselected tumors resected from 2009 to 2013. Three of 1176 (0.26%) "leiomyomas" and 1 of 44 (2.3%) "leiomyosarco...

2015
Won Beom Jung In Ja Park Joon Seon Song Kyung-Ja Cho Jin Cheon Kim

A glomus tumor is a very rare neoplasm consisting of cells that resemble the modified smooth muscle cells of normal glomus bodies. Here, we report a case of a 39-year-old male with multiple omental glomus tumors. The patient underwent a complete resection of the glomus tumors. This is a rare case of omental glomus tumors, and to our knowledge, this patient is the first with multiple omental glo...

Journal: :Journal of Clinical Investigation 2005

Journal: :International journal of advanced research 2021

Introduction: The leiomyoma of the urethra is rare. It a benign mesenchymal tumor that affects smooth muscle urethra. These tumors often occur in women childbearing age middle their appearance about 41 years old. Case report: Here we report case 37 old white woman with progressive dysuria nodule sensation vagina Conclusions: Leiomyoma tumor, common uterus but very rare His diagnosis rarely ment...

Journal: :Cancer research 1976
J B Jacobs S M Cohen M Arai G H Friedell O Bulay H K Urman

Occasional submucosal tumors of indeterminate origin and without definite connection to the overlying mucosa have been reported in mice given various carcinogenic agents. Two Swiss mice fed niridazole developed such tumors. Electron microscopy of 1 of the tumors revealed thin myofilaments with oval dense bodies, marginal dense plaques, and gap junctions, identifying the tumor as originating fro...

Journal: :Obstetrics and gynecology 1994
W A Peters D R Howard W A Andersen D C Figge

OBJECTIVE To determine whether tumors meeting the criteria of Hendrickson and Kempson for uterine smooth-muscle tumors of uncertain malignant potential have a natural history different from those of leiomyomas and leiomyosarcomas. METHODS Tumors with five to ten mitoses per ten high-power fields and with mild or moderate cellular atypia were classified as tumors of uncertain malignant potenti...

Journal: :European journal of gynaecological oncology 2011
S Hakverdi A Güngören M Yaldiz A U Hakverdi S Toprak

The expression of p16 as a tumor suppressor protein was evaluated in a retrospective analysis of paraffin-embedded tissue specimens of leiomyosarcoma (LMS), leiomyoma (LM) and normal myometrium. In this study, we investigated by immunohistochemistry p16 expression in 15 LMSs, 15 LMs and ten normal myometrium. Strong expression of p16 was found in 12 of the 15 LMSs and in three cases weak expres...

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