downs syndrome (ds), or trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. to date, the contribution of micrornas (mirnas) in ds has not been investigated. bioinformatic analyses demonstrate that human chromosome 21 (hsa21) harbors five mirna genes mir-99a, let-7c, mir-125b-2, mir-155 and mir-802. mirna expression profiling...

The development process that a group uses to design software is important for determining the success of a project. Although considerable research discusses processes best suited for large companies, this paper presents a case study of software development by a small group and considers the process taken towards the completion of a project. The collaborative undergraduate team project analyzed ...

We generalize Gel’fond’s criterion of algebraic independence to the context of a sequence of polynomials whose first derivatives take small values on large subsets of a fixed subgroup of C, instead of just one point (one extension deals with a subgroup of C).

This paper reviews research on grouping of students within classes and its effects on learning. Primary consideration is given to grouping and mixing students by ability, though consideration is also given to grouping and mixing students by ethnicity and gender as well as to research on the effects of group size. Results of meta-analyses of grouping show a small but meaningful advantage of form...

PURPOSE The goal of this study was to assess student perceptions of effective small group teaching during preclinical training in a medical school that promotes an integrated, systems-based undergraduate curriculum. In particular, students were asked to comment on small group goals, effective tutor behaviours, pedagogical materials and methods of evaluation. METHODS Six focus groups were held...

Presence in Collaborative Virtual Environments (CVEs) can be classified into personal presence and co-presence. Personal presence is having a feeling of “being there” in the CVE yourself. Co-presence is having a feeling that one is in the same place as the other participants, and that one is collaborating with real people. In this paper we present two experiments designed to investigate some of...

Small-bias, or -biased, spaces have found many applications in complexity theory, coding theory, and derandomization. We generalize the notion of small-bias spaces to the setting of group products. Besides being natural, our extension captures some of the difficulties in constructing pseudorandom generators for constant-width branching programs a longstanding open problem. We provide an efficie...

Assessment of groups in CSCL context is a challenging task fraught with many confounding factors collected and measured. Previous documented studies are by and large summative in nature and some process-oriented methods require time-intensive coding of qualitative data. This study attempts to resolve these problems for teachers to assess groups and give timely feedback. We first operationalize ...