Introduction: Successful radiotherapy requires the precise application of a radiation dose to cancerous tissue, which can be achieved by the design of proper treatment methods by radiotherapy physicists. Tasks performed by radiotherapy physicists include verifying the accuracy of dose calculations, correct treatment planning and the proper functioning of accelerators. They are...

AIM To compare dosimetry, efficacy, and toxicity of intensity-modulated radiation therapy (IMRT) with para-aortic field radiotherapy in patients with para-aortic lymph node (PALN) metastasis of cervical cancer. METHODS This prospective study examined 60 patients with cervical cancer with PALN metastasis who underwent whole-pelvis radiotherapy followed by brachytherapy between November 1, 2004...

background: the goals of the present research were to investigate the rectal dose during four chosen techniques of cervical cancer radiotherapy and to examine how accurately the treatment planning represents dose measurements, and it’s practicality for routine use as well as, to determine the homogeneity of dose in tumor volume. materials and methods: the study was carried out using a nepton 10...

OBJECTIVE Mimicking state-of-the-art patient radiotherapy with high-precision irradiators for small animals is expected to advance the understanding of dose-effect relationships and radiobiology in general. We work on the implementation of intensity-modulated radiotherapy-like irradiation schemes for small animals. As a first step, we present a fast analytical dose calculation algorithm for keV...

PURPOSE To demonstrate the feasibility of preoperative Hyperfractionated Accelerated RadioTherapy (preop-HART) in rectal cancer and to explain the rationales to switch from postoperative HART to preoperative HART. METHODS AND MATERIALS Fifty-two consecutive patients were introduced in successive Phase I trials since 1989. In trial 89-01, postoperative HART (48 Gy in 3 weeks) was applied in 20...

Background: In some patients with stage III small cell lung cancer (SCLC), it is found that the treatment mode of systemic chemotherapy followed by auxiliary radiotherapy better than early radiotherapy, but there no clear evidence-based medical explanation for this. This study was designed to retrospectively evaluate prognostic factors SCLC and explore best locally advanced SCLC.

The safety and efficacy of carbon-ion radiotherapy for advanced non-small cell lung cancer have not been established. We evaluated the clinical outcomes and dose-volume histogram parameters of carbon-ion radiotherapy compared with photon therapy in T2b-4N0M0 non-small cell lung cancer. Twenty-three patients were treated with carbon-ion radiotherapy between May 2011 and December 2015. Seven, 14,...