نتایج جستجو برای: sma dissection
تعداد نتایج: 60736 فیلتر نتایج به سال:
Social media analytics (SMA) is a rapidly emerging capability that provides organisations with the ability to analyse and interpret large amounts of online content to determine the attitudes and behaviours of people. The adoption and impact of SMA by businesses is still largely unexplored. In this paper we develop a framework, based on organisational motivation theory and the resourcebased view...
Spinal muscular atrophy (SMA) presents severe muscle weakness with limited motor neuron (MN) loss at an early stage, suggesting potential functional alterations in MNs that contribute to SMA symptom presentation. Using SMA induced pluripotent stem cells (iPSCs), we found that SMA MNs displayed hyperexcitability with increased membrane input resistance, hyperpolarized threshold, and larger actio...
Superior mesenteric artery (SMA) syndrome is an uncommon disease that results from SMA compression of the third portion of the duodenum. Patients with SMA syndrome present with upper gastrointestinal symptoms, such as nausea, vomiting, and abdominal pain. The diagnosis is usually made from an upper barium study or computed tomography. Typically, SMA syndrome is caused by a decreased aortomesent...
استفاده از آلیاژهای حافظه دار سوپرالاستیک (smas) به عنوان میلگرد در سازه های بتنی در میان پژوهشگران به تدریج در حال افزایش است. به دلیل تفاوت خواص مکانیکی sma در مقایسه با فولاد معمولی، استفاده از میلگرد smaدر بتن ممکن است تغییراتی در پاسخ سازه، تحت بار های لرزه ای به وجود آورد. در این مطالعه، تأثیر استفاده از میلگرد های sma در سازه های بتنی بر روی ساختمان های بتن مسلح 3، 6 و 8 طبقه به روش تحلی...
Chronic ventricular pressure overload can regulate expression of alpha-smooth muscle actin (SMA) in cardiac fibroblasts, but it is unclear if force alone or the concomitant activity of angiotensin II is the principal regulatory factor. To test if SMA mRNA and protein in rat cardiac fibroblasts are regulated directly by force, we first induced SMA expression in cultured cells and then applied ma...
BACKGROUND Spinal muscular atrophy (SMA) is caused by SMN1 dysfunction, and the copy number of SMN2 and NAIP can modify the phenotype of SMA. The aim of this study was to analyze the copy numbers and gene structures of SMA-related genes in Chinese SMA patients and unrelated healthy controls. METHODS Forty-two Chinese SMA patients and two hundred and twelve unrelated healthy Chinese individual...
linear low density polyethylene (lldpe) was blended with esterified styrene-maleic anhydride (esma) and its physical and mechanical properties were studied. styrene-maleic anhydride (sma) copolymer was synthesized by precipitation reaction. then, sma was esterified by 1-decanol in methylethyl ketone solvent. from the ftir spectrum of esma it is evident that the corresponding peaks of anhydride ...
Expression of alpha-smooth muscle actin (alpha-SMA) defines the phenotype of activated (myofibroblastic) hepatic stellate cells. These cells, but not quiescent stellate cells, have a high level of alpha-SMA and c-Myb expression, as well as increased c-Myb-binding activities to the proximal alpha-SMA E box. Therefore, we analyzed the role of c-Myb in alpha-SMA transcription and stellate cell act...
Spinal muscular atrophy (SMA) is an autosomal recessive disorder, which is the leading genetic cause of infantile death. SMA is the most common inherited motor neuron disease and occurs in approximately 1:6000 live births. The gene responsible for SMA is called Survival Motor Neuron-1 (SMN1). Interestingly, a human-specific copy gene is present on the same region of chromosome 5q, called SMN2. ...
The autosomal recessive neurodegenerative disease spinal muscular atrophy (SMA) results from low levels of survival motor neuron (SMN) protein; however, it is unclear how reduced SMN promotes SMA development. Here, we determined that ubiquitin-dependent pathways regulate neuromuscular pathology in SMA. Using mouse models of SMA, we observed widespread perturbations in ubiquitin homeostasis, inc...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید