Neurodegeneration, a common feature for many brain disorders, has severe consequences on the mental and physical health of an individual. Typically human neurodegenerative diseases are devastating illnesses that predominantly affect elderly people, progress slowly, and lead to disability and premature death; however they may occur at all ages. Despite extensive research and investments, current...

Energy consumption has become a major concern for all computing systems, from servers in data-centres to mobile phones. Processor manufacturers have reacted to this by implementing power-management mechanisms in the hardware and researchers have investigated how operating systems can make use of those mechanisms to minimise energy consumption. Much of this research has focused on a single class...

We present and study a new model for energy-aware and profit-oriented scheduling on a single processor. The processor features dynamic speed scaling as well as suspension to a sleep mode. Jobs arrive over time, are preemptable, and have different sizes, values, and deadlines. On the arrival of a new job, the scheduler may either accept or reject the job. Accepted jobs need a certain energy inve...

Moving cars give the illusion of slowing down in foggy conditions, because low contrast reduces perceived speed. A grey square that drifts horizontally across a surround of black and white vertical stripes appears to stop and start as it crosses each stripe, because its contrast keeps changing. A moving square whose vertical and horizontal edges have different contrasts will show illusory disto...

We investigate whether the recent slow-down of Whillans Ice Stream (WIS),West Antarctica, may lead to its complete stoppage in the near future, using a numerical model. Basal resistance to ice-stream motion is represented by a continuous till layer whose strength changes in response to basal melting and freezing.We implement a basal drainage system, which acts to hinder ice-stream stoppage thro...

It was shown in C. elegans that life-long treatments with low level of the prooxidant paraquat increased reactive oxygen species (ROS), which then acted as the signal to slow down aging by activating the intrinsic apoptosis pathway. And deficiencies of the electron transport chain subunits increased longevity through similar mechanisms. We surprisingly found that ROS were downand up-regulated r...

Search for evidence of trend slow-down in the long-term TOMS/SBUV total ozone data record: the importance of instrument drift uncertainty and fingerprint detection R. S. Stolarski and S. Frith NASA Goddard Space Flight Center, Greenbelt, MD 20771, USA Science Systems and Applications, Inc., Lanham, MD 20706, USA Received: 23 January 2006 – Accepted: 28 February 2006 – Published: 16 May 2006 Cor...

Light has a profound effect on plant growth and development. Red and blue light best drive photosynthetic metabolism, so it is no surprise that these light qualities are particularly efficient in advancing the developmental characteristics associated with autotrophic growth habits. Photosynthetically inefficient light qualities also impart important environmental information to a developing pla...

We consider two variants of a two-station tandem network with blocking. In both variants the first server ceases to work when the queue length at the second station hits a ‘blocking threshold.’ In addition, in variant 2 the first server decreases its service rate when the second queue exceeds a ‘slow-down threshold,’ which is smaller than the blocking level. In both variants the arrival process...

Leading neural models of visual word recognition assume that letter rotation slows down the conversion of the visual input to a stable orthographic representation (e.g., local detectors combination model; Dehaene, Cohen, Sigman, & Vinckier, 2005, Trends in Cognitive Sciences, 9, 335-341). If this premise is true, briefly presented rotated primes should be less effective at activating word repre...