PURPOSE Neoadjuvant chemotherapy (NAC) has been recently used to downstage breast cancer. However, in patients with initial axillary lymph node (ALN) metastasis, ALN dissection regardless of the NAC response remains the standard treatment. The purpose of this study was to identify the feasibility and accuracy of sentinel lymph node biopsy (SLNB) after NAC in patients with ALN metastasis at diag...

BACKGROUND The diagnostic performance of indocyanine green (ICG) fluorescence-guided sentinel lymph node biopsy (SLNB) for the presence of metastases in breast cancer remains unclear. OBJECTIVE We performed a meta-analysis to investigate the diagnostic performance of ICG-guided SLNB. METHODS Eligible studies were identified from searches of the databases PubMed and EMBASE up to September 20...

The Permanente Journal/ Spring 2007/ Volume 11 No. 2 Since the Halsted radical mastectomy was introduced in 1894, breast cancer treatment has undergone major changes. More than a century later, breast conserving surgery is now accepted in the treatment armamentarium of early breast cancer. However, the role of axillary lymph node dissection (ALND) in breast cancer treatment continues to be cont...

BACKGROUND Ultrasound (sonography, B-mode sonography, ultrasonography) examination improves the sensitivity in more than 25% compared to the clinical palpation, especially after surgery on the regional lymph node area. OBJECTIVE To evaluate the distribution of metastases during follow-up in the draining lymph node areas from the scar of primary to regional lymph nodes (head and neck, supracla...

background: in an attempt to reduce the risk of developing lymphedema following breast cancer surgery, some researchers suggested that by identifying and preserving the lymphatic plexus which drains ipsilateral arm we can minimize the risk of lymphedema. the procedure is known as axillary reverse mapping (arm). in the current study, we investigated the oncological safety of this technique. meth...

BACKGROUND: The role of sentinel lymph node biopsy (SLNB) in patients with an initial diagnosis of ductal carcinoma in situ (DCIS) has not been well defined. The purpose of our study was to determine when the risk of finding invasive disease on final pathology in patients with an initial diagnosis of DCIS was sufficiently high to justify use of SLNB. STUDY DESIGN: The records of 398 consecutive...

BACKGROUND The sentinel lymph node (SLN) is defined as the first draining node from the primary lesion, and it has proven to be a good indicator of the metastatic status of regional lymph nodes in solid tumors. The aim of this study was to evaluate the clinical application of SLN biopsy (SLNB) in papillary thyroid carcinoma (PTC) with occult lymph nodes. METHODS From April 2006 to October 201...

PURPOSE Compare the lymphatic flow in the arm after breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphos-cintigraphy (LS). PATIENTS AND METHODS A cross-sectional study with 39 women >18 years who underwent surgical treatment for unilateral breast cancer and manipulation of the axillary lymph node chain through either ALND or SL...

The role of axillary surgery for the treatment of primary breast cancer is in a process of constant change. During the last decade, axillary dissection with removal of at least 10 lymph nodes (ALD) was replaced by sentinel lymph node biopsy (SLNB) as a staging procedure. Since then, the indication for SLNB rapidly expanded. Today's surgical strategies aim to minimize the rate of patients with a...

While significant advances have been made in the past decade in the etiopathogenesis of differentiated thyroid cancer (DTC),1 advances in surgery have not been relevant. Thus, robot-assisted cervicoscopic techniques or procedures using approaches different from the conventional transverse cervicotomy have been developed.2 The practical value of these approaches is however very limited. One of t...