AIM Chordomas are rare, slow growing but locally aggressive malignancies of the axial skeleton. Skull base chordomas, due to their intricate anatomical localization, pose significant challenges to managing physicians. In classical and chondroid chordomas, the disease course cannot be reliably determined using only morphological criteria. Brachyury (T Gene) was shown to play a central role in ch...

Background Aneurysm formation after stereotactic irradiation of skull base tumors is rare. The formation and rupture of an internal carotid artery (ICA) aneurysm in a patient with skull base Ewing sarcoma/primitive neuroectodermal tumor (PNET), who underwent surgery followed by multiple courses of intensity-modulated radiation therapy (IMRT) and chemotherapy, is described. Case Description A 25...

Objective Hemorrhage control in skull base surgery is critical but hindered by the lack of instruments suitable for coagulating structural curves and corners. The main impediment is that most of the instruments currently used are right-angled and unsuitable because anatomical and pathologic structures are three-dimensional objects having complex curves and corners. In this article, we present a...

Introduction: Chordoma is a rare bone tumor, which develops mainly from the sacrum, the base of skull, or spine. Surgery + radiotherapy (if necessary) the standard treatment. Data on chordoma are scarce in this region, and thus, here we summarized 9 patients with this tumor whom treated institute. Material: Nine chordoma were summarized, who National Institute of Oncology Rabat between 201...

skull metastasis from hepatocellular carcinoma, specially as the first presentation is very rare. we report a case with a history of head trauma in bam earthquake and craniotomy due to lytic tumor of the skull, presented with upper gastrointestinal symptoms which hepatocellular carcinoma with skull metastasis was revealed .the patient was infected with hepatitis b virus without cirrhosis.

A 65-year-old male presented with a 3-year history of orbital symptoms. An imaging-based diagnosis of fibrous dysplasia involving the skull base was made at another institution. CT showed a diffuse sinonasal mass and ground-glass appearance of the bones of the anterior skull base with bony defects and mucocele formation. MRI demonstrated an accompanying intracranial and orbital rind of soft tis...

chondroma is a benign tumor which mostly occurs in extremities but also sometimes in brain. most intracranial chondromas arise from skull base, but chondroma of falx origin is a rare circumstance. indeed, the intracranial chondromas rise from falx is mostly in relation with syndromic disorders such as mafucci's syndrome or ollier's syndrome. here, we reported a rare case of falxian intracranial...

The authors report their experience with image-based preoperative vascular and neural element segmentation with three-dimensional (3D) reconstruction for intraoperative guidance in ten patients undergoing surgery for skull base tumor resection. In all cases, the 3D segmented structures were correlated to the correspondent intraoperative findings with the aid of neuronavigation. They conclude th...

several lesions (inflammatory, neoplastic and congenital) can involve in the skull base. the role of imaging is to detect the location and extension of lesion, determine mass and mass like lesions, differentiate benign from malignant tumors, detect invasion to adjacent structures and make decision in surgical planning. skull base divides to anterior, middle and posterior cranial fossa and some ...