A protocol for percutaneous absorption studies has been validated, based on the use of reconstructed human epidermis (RHE) and aqueous solutions of test substances. However, it is often the case that it is more-complex formulations of drugs or chemicals which will make contact with the skin surface. To investigate whether RHE and the reconstructed full-thickness skin model (FT-model) can be use...

In this paper we present a skin color approach for fast and accurate face detection which combines skin color learning and image segmentation. This approach starts from a coarse segmentation which provides regions of homogeneous statistical color distribution. Some regions represent parts of human skin and are selected by minimizing an error between the color distribution of each region and the...

BACKGROUND Rhinoplasty remains one of the most challenging operations, as exemplified in the Middle Eastern patient. The ill-defined, droopy tip, wide and high dorsum, and thick skin envelope mandate meticulous attention to preoperative evaluation and efficacious yet safe surgical maneuvers. The authors provide a systematic approach to evaluation and improvement of surgical outcomes in this pat...

Skin photodamage, which is induced by ultraviolet (UV) radiation, a prevalent cause of skin damage. In this study, transdermal drug delivery system developed for the topical treatment composed tetrahedral framework nucleic acids (tFNAs) and lipoic acid (LA). The tFNAs-LA (TLA) nanocomposite exhibits excellent biocompatibility, as well antioxidant, anti-apoptotic, anti-inflammatory capabilities....

Insertion behaviour of microneedle (MN) arrays depends upon the mechanical properties of the skin and, MN geometry and distribution in an array. In addressing this issue, this paper studies MN array insertion mechanism into skin and provides a simple quantitative basis to relate the insertion force with distance between two MNs. The presented framework is based on drawing an analogy between a b...

the aim of the this work was to determine the finger patterns, finger ridge count (frc), total finger ridge count (tfrc), and asymmetry of finger ridge count (afrc) of an iranian girl (aged 13 years) affected with congenital cutis laxa (ccl).the fingerprints of the first phalanx of both hands were taken by using the standard method (stamp ink). the fingerprints were classified according to the ...

background: as the early and accurate diagnosis of all diseases, including skin disorders directly influences the duration of treatment and its costs, which may be a significant burden, it is very important for physicians to be familiar with all types of diseases, especially those with a higher incidence in population. considering that disease patterns vary from region to region and there is no...

background:  scabies is an ectoparasitic infection, which occurs because of direct skin-to skin contact. the ideal treatment modality is still unclear and further research on this topic is warranted. the aim of the study was to com­pare the efficacy and safety of the topical scabicides: permethrin, crotamiton and sulfur ointment. methods: fifty four patients with diagnosed scabies were randomly...

objective(s):the objective of this study was to find a stable microemulsion vehicle for transdermal delivery of ibuprofen to improve the skin permeability. materials and methods: microemulsion was prepared using different sorts of oils, surfactants and co-surfactants. pseudo-ternary phase diagrams were used to evaluate the microemulsion domain. the effects of oleic acid and surfactant mixture o...

background: one of the most common cancers is skin cancer worldwide. since incidence and cost of treatment of the cancer are increasing, it is necessary to further investigate to prevent and control this disease. this study aimed to determine skin cancer trend and epidemiology in iran. methods: this study was done based on existing data. data used in this study were obtained from a national reg...