BACKGROUND The importance of postoperative gastrointestinal function recovery is being increasingly recognized. In this multi-center randomized controlled study, we evaluated the efficacy and safety of Evodia hot compress (ECS) plus electro-acupuncture (EA) for patients who developed postoperative gastrointestinal tract dysfunction after abdominal surgery. METHODS 1009 patients who developed ...

BACKGROUND Evidence on the impact of expectancy on acupuncture treatment response is conflicting. OBJECTIVES This secondary analysis of a randomized sham-controlled trial on acupuncture for menopausal hot flashes investigated whether treatment expectancy score was associated with hot flash score at end-of-treatment. Secondary analyses investigated whether there were associations between other...

OBJECTIVE To estimate the effect of escitalopram (10-20 mg/d) versus placebo for reducing hot flash interference in daily life and understand correlates and predictors of reductions in hot flash interference, a key measure of quality of life. DESIGN Multisite, randomized, double-blind, placebo-controlled clinical trial. SETTING MsFLASH clinical sites in Boston, Indianapolis, Oakland, and Ph...

Meiotic recombination, crucial for proper chromosome segregation and genome evolution, is initiated by programmed DNA double-strand breaks (DSBs) in yeasts and likely all sexually reproducing species. In fission yeast, DSBs occur up to hundreds of times more frequently at special sites, called hot spots, than in other regions of the genome. What distinguishes hot spots from cold regions is an u...

PURPOSE/OBJECTIVES To evaluate the intermediate term efficacy and toxicity of the use of venlafaxine for the control of hot flashes. DESIGN An open-label continuation phase study following a double-blind, randomized, placebo-controlled clinical trial that tested three doses of venlafaxine for the control of hot flashes. SETTING North Central Cancer Treatment Group institutions. SAMPLE 102...

objective: the beneficial effects of clove on toothache have been well documented. we have also previously shown the analgesic effects of clove essential oil. the present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. the possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. materials a...

morphine and tramadol which have analgesic effects can be administered acutely or chronically. this study tried to investigate the effect of these drugs at various times by using different methods of administration (intraperitoneal, oral, acute and chronic). sixty adult female rats were divided into six groups. they received saline, morphine or tramadol (20 to 125 mg/kg) daily for 15 days. a ho...

objective(s):reduction of pharmacological effectiveness or tolerance appears following repeated administration of many analgesic drugs. we investigated tolerance to anti-nociceptive effects of orexin-a, an endogenous potent analgesic peptide using the hot-plate test.materials and methods:orexin-a was microinjected icv (intracerebroventricular) with an interval of 12 hr for 7 continuous days and...

introduction natural and artificial radionuclides are the main sources of human radiation exposure. these radionuclides, which are present in the environment, can be dissolved into water. evidence suggests that radionuclides being entered the human body through drinking or hot spring water can be harmful for human health. materials and methods in this study,10 samples were collected from ground...