The 3' nontranslated region of the genomes of Sindbis virus (SIN) and other alphaviruses carries several repeat sequence elements (RSEs) as well as a 19-nucleotide (nt) conserved sequence element (3'CSE). The 3'CSE and the adjoining poly(A) tail of the SIN genome are thought to act as viral promoters for negative-sense RNA synthesis and genome replication. Eight different SIN isolates that carr...

UNLABELLED BACKGROUND The 11S globulin Sin a 2 is a marker to predict severity of symptoms in mustard allergic patients. The potential implication of Sin a 2 in cross-reactivity with tree nuts and peanut has not been investigated so far. In this work, we studied at the IgG and IgE level the involvement of the 11S globulin Sin a 2 in cross-reactivity among mustard, tree nuts and peanut. MET...

What was originally intended to be a characterization of an “ideal” extensive reading (ER) approach, however, has been taken to an almost religious quality with some practitioners who firmly believe that any approach that deviates from these guidelines is not truly “extensive reading.” This, I have found, is one of the most frequent objections to using the MReader.org quiz program among teacher...

PURPOSE Recently, the application of replication-competent viruses has been studied as anticancer agents. Sindbis virus (SIN) is an RNA virus that belongs to the Alphavirus genus in the Togaviridae virus family. The AR339 strain of SIN has not been reported to induce any serious disease to humans. EXPERIMENTAL DESIGN In this study, we evaluated the feasibility of the replication-competent SIN...

Now, let (u, v) = Rα(θ, φ′). Here, Rα = Ry(α). We omit the z rotation since that does not affect Yl0 which has no azimuthal dependence. The vector corresponding to coordinates (u, v) is then given by   sinu cos v sinu sin v cos u   =   cosα 0 sinα 0 1 0 − sinα 0 cosα     sin θ′ cosφ′ sin θ′ sinφ′ cos θ′   =   cosα sin θ′ cosφ′ + sinα cos θ′ sin θ′ sinφ′ cosα cos θ′ + sinα sin θ′ (...

El refuerzo del régimen de semilibertad penitenciario constituye a día hoy uno los grandes objetivos sistemas penitenciarios. La aprobación reciente una Instrucción para el acceso directo al medio abierto por la Administración Penitenciaria española nos permite reflexionar sobre distintos aspectos que implica esta concreta modalidad ejecución penal. En este caso necesidad y concepto reinserción...