We describe a dual-modality laser scanning endomicroscope that provides simultaneous fluorescence contrast based on confocal laser endomicroscopy (CLE) and phase-gradient contrast based on scanning oblique back-scattering microscopy (sOBM). The probe consists of a 2.6mm-diameter micro-objective attached to a 30,000-core flexible fiber bundle. The dual contrasts are inherently co-registered, pro...

We propose a new dual treatment strategy for venous ulcer, consisting in simultaneous modulation of matrix metalloproteinases (MMPs) and heat shock proteins (HSPs) in the wound. One treatment method which can efficiently modulate both these substances is based on the application of dual-frequency ultrasound (LDM). This strategy was checked in a pilot study on 10 patients with chronic venous ulc...

Several sites in the United States have groundwater contaminated with mixtures of high explosives and chlorinated solvents. This research examined the ability of two microbial cultures (anaerobic sludge and a facultative enrichment culture) to biodegrade singleand dual-contaminant mixtures of trichloroethene (TCE) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) under anaerobic conditions. In ...

Objective(s): Use of a positron emission tomography (PET)/single-photonemission computed tomography (SPECT) system facilitates the simultaneousacquisition of images with fluorine-18 fluorodeoxyglucose (18F-FDG) andtechnetium (99mTc)-tetrofosmin. However, 18F has a short half-life, and 511keV Compton-scattered photons are detected in the 99mTc energy window.Therefore, in this study, we aimed to ...

The present study offers a new method based on CdSe quantum dots (QDs) for simultaneous separation and determination of trace levels of heparin (Hep) in human serum samples. In this technique, CdSe QDs perform two different functions in Hep analysis process. Mercaptoacetic acid-capped red CdSe QDs (λex=690 nm) are conjugated to Hep and the Hep-QD conjugation is then used as an extraction tool ...

In dual-task situations, interference between two simultaneous tasks impairs performance. With practice, however, this impairment can be reduced. To identify mechanisms leading to a practice-related improvement in sensorimotor dual tasks, the present review applied the following general hypothesis: Sources that impair dual-task performance at the beginning of practice are associated with mechan...

Gait impairments in Parkinson's disease (PD) are exacerbated under dual-task conditions requiring the simultaneous performance of cognitive or motor tasks. Dual-task walking deficits impact functional mobility, which often requires walking while performing concurrent tasks such as talking or carrying an object. The consequences of gait impairments in PD are significant and include increased dis...

A simple self-seeding scheme is developed to generate tunable dual-wavelength optical short pulses in a flexible manner and with an increased wavelength-tuning range. The wavelength selection and tuning are achieved by simultaneous use of a fiber Bragg grating and a tunable optical filter. The side-mode suppression ratio of the output pulses is better than 30 dB over a wavelength-tuning range o...

This paper is concerned with some methods that attempt to provide simultaneous representation of dual relationships, such as ties of membership that connect persons and groups, or connections between organizations and agendas. We focus on vector space and lattice representations, and on techniques for simplifying the structure of dual networks. We demonstrate some fundamental similarities among...