The stability constant Kf for the complexation of Ag(Ⅰ) metal ion with Midodrine hydrochloride were determinedby spectrophotometric method at room temperature .The colored complexes measured 300 nm. found to be 5.47 by mole ratio method. stoichiometry formed between drug and Ag (Ⅰ) are 1:1 M/L ratio. Silver conjugated Nano synthesized characterized UV/Visible spectroscopy, SEM, XRD FT-IR. spect...

Nanoparticle toxicology, an emergent field, works toward establishing the hazard of nanoparticles, and therefore their potential risk, in light of the increased use and likelihood of exposure. Analytical chemists can provide an essential tool kit for the advancement of this field by exploiting expertise in sample complexity and preparation as well as method and technology development. Herein, w...

The ultrafast nonlinear optical response of a single metal nanoparticle is investigated by combining a high-sensitivity femtosecond pump-probe setup with a spatial modulation microscope. Experiments are performed on 20 and 30 nm silver nanospheres, in situ characterized via their optical linear extinction spectrum. The measured transient response permits investigation of the electron-phonon ene...

We investigate binding and plasmonic coupling between optically trapped 80 nm silver spheres using a combination of spectroscopic sensing and 3D interferometric laser particle tracking on a 1 μs time scale. We demonstrate that nanoparticle coupling can be either spontaneous or induced by another particle through confinement of diffusion. We reveal ultrafast entries and exits of nanoparticles in...

We theoretically investigate the tuning of Photonic band gaps in one dimensional photonic crystals based on Nano composite of silver nanoparticle embedded in SiO2 by applying electric field. In addition, the tuning can be done by considering the filling fraction and the radius of the nanoparticle. The evolution of these results to provide new possibilities of designing the desired photonic crys...

A method for analyzing combinatorial DNA arrays using oligonucleotide-modified gold nanoparticle probes and a conventional flatbed scanner is described here. Labeling oligonucleotide targets with nanoparticle rather than fluorophore probes substantially alters the melting profiles of the targets from an array substrate. This difference permits the discrimination of an oligonucleotide sequence f...

We demonstrate that by combining silver nanoparticles and structured gold SSV surfaces the SERS for those molecules that bridge the nanoparticle-cavity gap is preferentially enhanced using 4-mercaptoaniline and 4-mercaptobenzoic acid as examples.

A facile supramolecular approach to prepare surface functionalized silver nanoparticle conjugates has been established and their enhanced molecular recognition features have been explored to demonstrate the uptake and stimulus responsive release of a phototherapeutic porphyrin dye, the TMPyP.

DNA-silver nanoparticle (AgNP) conjugates were facilely prepared through a one-step method, and then used for the quantitative detection of HIV DNA with a sandwich strategy based on their strong plasmon resonance scattering signals.