This paper provides an overview of the current version of SIGA, a system that supports the organization of information retrieval (IR) evaluations. SIGA was recently used in Págico, an evaluation contest where both automatic and human participants competed to find answers to 150 topics in the Portuguese Wikipedia, and we describe its new capabilities in this context as well as provide preliminar...

It was recognized that in human milk some amounts of lactoferrin (LF) were naturally bound to secretory IgA (sIgA). Since not only secretory component (SC) but also LF was released from sIgA by disulfide bond cleavage, it is conceivable that LF is naturally bound to IgA as well as SC. An in vitro binding test to LF and IgA was performed and the binding was confirmed by the use of an IgA-Sepharo...

prostatitis; male chlamydial infections halamydia trachomatis (C.t.) has been involved in variety of pathological conditions of the female and male genital tracts. Chronic female persistent infections due to this microorganism have been recently investigated, but the role of C.t. has not been completely clarified especially in acute and chronic pathologies of the male genital tract. The immunoc...

The present study aimed to determine changes in the concentration of secretory immunoglobulin A (SIgA) and interleukin 6 (IL-6) in the saliva of patients with oral cancer, to evaluate the abnormal expression of cluster of differentiation (CD) 1a, CD83, CD80 and CD86 on dendritic cells (DCs) of oral cancer tissues and to discuss the interaction between SIgA, IL-6 and DCs in oral cancer. A total ...

<b><i>Background:</i></b> IgA nephropathy (IgAN) is characterized by the mesangial deposition of pathogenic IgA. We previously detected secretory (SIgA) in mesangium about one-third IgAN patients. Tubulointerstitial injury has an important role development IgAN. However, relationship between SIgA and tubulointerstitial damage currently unclear. In this work, mesangial-tu...

I read the recent report on effect of acupuncture on salivary immunoglobulin A by Matsubara et al with a great interest.1 Matsubara et al concluded that ‘Acupuncture treatment may attenuate the decrease in SIgA level induced by intense exercise.’1 Indeed, there are some previous similar reports on this topic. Akimoto et al recently found that ‘Exercise-induced decrease of salivary SIgA and incr...

Sigma factors are RNA polymerase subunits engaged in promoter recognition and DNA strand separation during transcription initiation in bacteria. Primary sigma factors are responsible for the expression of housekeeping genes and are essential for survival. RpoD, the primary sigma factor of Escherichia coli, a γ-proteobacteria, recognizes consensus promoter sequences highly similar to those of so...

Very little is known about the effects of gestational diabetes mellitus (GDM) on lactation and milk components. Recent reports suggested that hyperglycemia during pregnancy was associated with altered breast milk immune factors. Human milk oligosaccharides (HMOs) and N-glycans of milk immune-modulatory proteins are implicated in modulation of infant immunity. The objective of the current study ...

The MADS box transcription factor SrfA is required for spore differentiation in Dictyostelium discoideum. srfA null strains form rounded spores that do not resist adverse environmental conditions. Five genes whose expression is dependent on SrfA have been isolated by differential hybridization. One of these genes, sigC, is identical to phg1b, previously characterized in mutants with altered adh...

Resumo. Quando ocorrem falhas de equipamento em plantas industriais complexas, o sistema de automação e controle gera uma grande quantidade de eventos e alarmes que podem confundir os operadores e induzi-los a tomar decisões erradas – o tempo para tomada de decisão é muito curto e a quantidade de informação gerada é muito grande, sendo impossível que o operador consiga ler todas antes de tomar ...