Objective: Shigellosis is an important gastrointestinal infection in tropical and temperate countries. The purpose of this investigation was to determine the prevalence and antibiotic resistance of the different serotypes of Shigella species among nursery and primary school children with diarrhoea in two semi-urban communities in Nigeria. Methods:The isolates were characterized using standard b...

The clinical and pathological findings in a group of 260 homosexual men comprising 10% of a private proctologic practice are reviewed. A clinical pattern of anorectal and colon diseases encountered with unusual frequency in these homosexual patients is termed the gay bowel syndrome. The clinical diagnoses in decreasing order of frequency include condyloma acuminata, hemorrhoids, nonspecific pro...

In Vietnam, shigellosis, typhoid fever, and cholera are important enteric diseases. To determine their magnitude and geographical distribution, and explore associated risk factors, we examined national surveillance data from 1991 to 2001 and potential ecological determinants. Average annual incidence rates were calculated and mapped for each province. Bivariate and multiple regression analyses ...

AIMS To assess quantitatively both the morphological changes in the rectal mucosa and the changes in the relative frequency of IgA and IgG subclass producing cells found in the rectal mucosa during the acute phase of shigellosis and at convalescence. METHODS Rectal biopsies from 25 Shigella dysenteriae 1 infected patients, 10 Shigella flexneri infected patients, and 40 uninfected controls wer...

The effect of human recombinant interleukin-1 receptor antagonist on intestinal inflammation, tissue destruction, and bacterial invasion during experimental shigellosis caused by Shigella flexneri was studied in the rabbit-ligated loop infection model. Intravenous infusion of the inhibitor at a dose of 2 mg/kg per h, was initiated 30 min before intestinal loops were ligated and infected, and co...

Shigellosis is a disease which is recognized as a global problem with high morbidity in developing countries. Antimicrobial resistant Shigel/a spp. have been found in many parts of the world and resistant isolates have also been reported in Canada<304>. Antimicrobial therapy of some cases of shigellosis is indicated for several clinical and epidemiologic reasons<5•6>. Physicians who· elect...

This is a review of existing data on the burden of shigellosis in Thailand to determine trends, vulnerable groups, predominant species and serotypes, and antimicrobial resistance patterns. Diarrhoea and dysentery morbidity and mortality data from 1991 to 1999 was collected from the routine surveillance system and demographic data from the government census. International and local literature pu...

INTRODUCTION Shigellosis is still a major public health problem in sub-Saharan countries, especially among children. METHODOLOGY The prevalence of shigellosis in children presenting with diarrhoea in the Complexe Pédiatrique de Bangui, Central African Republic, was determined. Stools were analyzed in the bacteriology laboratory of the Institut Pasteur de Bangui, Central African Republic, wher...