Growth hormone-activated STAT5b is an essential regulator of sex-differential gene expression in mouse liver; however, its impact on hepatic and epigenetic responses poorly understood. Here, we found a substantial, albeit incomplete loss liver sex bias hepatocyte-specific STAT5a/STAT5b (collectively, STAT5)-deficient liver. In male liver, many male-biased genes were downregulated direct associa...

In this study, we investigated the age-dependent changes in reproductive efficiency of Kutum, Rutilus frisii  caught  from Shirood River,  the Southern Caspian Sea (Mazandaran Province, Iran). Age-dependent reproductive performance of brooders was assayed on two age and sex groups. Results revealed thatthere were no significant differences in sperm characteristics between age groups. All female...

Two-sex populations are usually studied through frequency-dependent models that describe how sex ratio affects mating, recruitment and population growth. However, in two-sex populations, mating and recruitment should also be affected by density and by its interactions with the sex ratio. Density may have positive effects on mating (Allee effects) but negative effects on other demographic proces...

Two-sex populations are usually studied through frequency-dependent models that describe how sex ratio affects mating, recruitment and population growth. However, in two-sex populations, mating and recruitment should also be affected by density and by its interactions with the sex ratio. Density may have positive effects on mating (Allee effects) but negative effects on other demographic proces...

Coxibs such as celecoxib, rofecoxib and valdecoxib are introduced as selective COX-2 inhibitors to the market. It has been reported that inhibition of COX-2 beside traditional effects of NSAIDs, reduces the risk of colorectal, breast and lung cancers and slow the progress of Alzheimer’s disease. Zarghi et al. reported 8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-carboxylic acid (AZGH 102) ...

Balanced (1 to 1) sex ratios are thought to evolve by a process known as frequency- dependent selection of the minority sex. Five populations of a fish with genetically based variation in temperature-dependent sex determination were maintained for 5 to 6 years in artificial constant-temperature environments that initially caused the sex ratio to be highly skewed. Increases in the proportion of ...