background: more than 40% of infertilities are due to endometriosis. ultrustructural and histochemical study of endometrium will help to clarify the etiology of endometriosis. objective: the aim of the present study was to investigate the ultrastructure and occurrence of apoptosis in endometrial cells of women with or without endometriosis. materials and methods: in the present case-control stu...

Abstract Background: Recent studies have suggested that oxidative stress (OS) may have a contribution in the pathogenesis of endometriosis. However, the results of previous studies regarding OS in endometriosis are controversial. The objective of this study was to compare the serum levels of OS markers in endometriosis versus the control group. Methods: This case-control study was carried out...

Endometriosis is a common gynecological condition with complex etiology defined by the presence of endometrial glands and stroma outside the womb. Endometriosis is a common cause of both cyclic and chronic pelvic pain, reduced fertility, and reduced quality-of-life. Diagnosis and treatment of endometriosis is, on average, delayed by 7-10 years from the onset of symptoms. Absence of a timely and...

objective: endometriosis affects women’s physical and mental wellbeing. symptoms include dyspareunia, dysmenorrhea, pelvic pain, and infertility. the purpose of this study is to assess the correlation between some relevant factors and symptoms and risk of an endometriosis diagnosis in infertile women. materials and methods: a retrospective study of 1282 surgical patients in an infertility insti...

BACKGROUND In order to obtain a lead of the pathophysiology of endometriosis, genome-wide expressional analyses of eutopic and ectopic endometrium have earlier been reported, however, the effects of stages of severity and phases of menstrual cycle on expressional profiles have not been examined. The effect of genetic heterogeneity and fertility history on transcriptional activity was also not c...

endometriosis is a painful reproductive disease afflicting about up to 20% of women. it is one of the most frequent benign gynaecological diseases, however, little is known about the pathological of endometriosis. over the past decade, high-throughput proteomics technologies have evolved considerably and have become increasingly more commonly applied to the investigation of female reproductive ...

background: the pro-inflammatory cytokine, tumor necrosis factor-alpha (tnf-α), is a pathogenic element for a number of disorders. previous studies have reported that the -1031 t/c and -238 g/a polymorphisms in the promoter region of the tnf-α gene are important factors in reproductive-related disorders. one of the most common gynecological diseases of women during the reproductive years is end...

background: endometriosis influenced by both genetic and environmental factors. associations of glutathione s-transferases (gsts) genes polymorphisms in endometriosis have been investigated by various researchers; however, the results are not consistent.objective: we examined the associations of gstm1 and gstt1 null genotypes and gstp1 313 a/g polymorphisms with endometriosis in an iranian popu...

STUDY QUESTION How do fully-comprehensive patient-centred descriptions of the symptoms of endometriosis compare with the physicians' description of the symptoms? SUMMARY ANSWER The description of the painful symptoms due to endometriosis is based on numerous distinct parameters. The way these are used to describe symptoms and the way they are interpreted varies significantly between patients ...

Background: Endometriosis as one of the most common health problems of women during their reproductive age, affects 2.5-3.3% of women. Endometriosis may be asymptomatic or associated with dysmenorrheal symptoms, dyspareunia, pelvic pain, abnormal uterine bleeding and infertility. The objective of present study was to determine the risk factors related to endometriosis among Iranian infertile wo...