conclusion adrenal iron in β-tm can be reliably measured in 3 tesla mri. the results highlight the absence of correlation between adrenal iron deposition both with serum ferritin and hepatic iron. results among patients, there was no significant correlation between plasma ferritin and adrenal t2*. significant difference was detected among t2* values of adrenals between the patient and control g...

BACKGROUND Serum ferritin is a frequently used marker of iron status in dialysis patients. Iron administration is to be withheld for ferritin values >800 ng/ml according to K/DOQI guidelines. We hypothesized that such non-iron-related factors as elements of the malnutrition-inflammation complex syndrome (MICS) may increase serum ferritin concentration independently of iron status. METHODS We ...

OBJECTIVES An increase in serum ferritin and levels of the cleaved soluble form of transferrin receptor (sTfR) are related to several metabolic conditions. We evaluated the relationship between body iron status indicators, including ferritin and sTfR, and insulin resistance and metabolic syndrome (MetS) in Korean children. METHODS A cross-sectional study was conducted on 1350 children in Kore...

BACKGROUND Oxidative stress has a major pathogenic role for liver damage following chronic hepatitis B. Glutathione peroxidase (Gpx) is necessary in oxidative state mechanism that is generally down-regulated by Hepatitis B virus (HBV) infection. On the other hand, disorders of iron homeostasis have been found out in HBV infected patients. Therefore, the objective of this study was to assess the...

We recently reported that parenteral iron therapy is associated with a characteristic pattern of iron staining on bone marrow aspirate smears. We now present clinical information from 6 patients who received parenteral iron and, at one or more points in follow-up, were found to have low or borderline low serum ferritin levels and/or serum iron levels, even though marrow aspirate smears revealed...

BACKGROUND Gastric bypass surgery is a highly effective therapy for long-term weight loss in severely obese patients, but carries significant perioperative risks including infection, wound dehiscence, and leaks from staple breakdown. Iron status can affect immune function and wound healing, thus may influence peri-operative complications. Common mutations in the HFE gene, the gene responsible f...

OBJECTIVE To evaluate the relation between iron status and physical working capacity, and to assess the effect of oral iron treatment on these variables, in athletes with borderline iron status. METHODS Blood haemoglobin (Hb), packed cell volume (PCV), red blood cell count (RBC), serum iron, total iron binding capacity (TIBC), and ferritin determinations were compared in 71 male and 18 female...

iron is a pro-oxidant cofactor that may be linked to atherosclerosis progression. free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids. reduction of body iron stores secondary to blood donation has been hypothesized to reduce lipid peroxidation. the aim of this study was to evaluate the association between blood donation and antioxidant enzymes a...