1. By the use of the silver-silver chloride electrode, measurements have been made of the chloride ion concentrations of 1 per cent solutions of five proteins, containing from 0.001 N to 0.1 N hydrochloric acid. The hydrogen ion concentrations of the same solutions have been measured by the use of the hydrogen electrode. 2. The measurements indicate that the chlorides of gelatin, egg albumin, c...

The stability of imipenem in 0.9% sodium chloride and in human serum was measured at controlled temperatures over time. The degradation was characterized by a first-order process and was consistent with an apparent hydrolysis reaction.

Editors,—I read with interest the article by Ruttmann, James and Aronson1 concerning haemodilution with hydroxethyl starch and normal saline. However, I disagree with their conclusion that they have shown that haemodilution per se exerted a procoagulant effect in both groups. Instead, I propose that their conclusion should be that they demonstrated that haemodilution with normal saline resulted...

Many modifications have been suggested for the determination of chloride in blood and other body fluids. The simplest and most thoroughly studied is a method proposed by Van Slyke (1) involving ashing of serum with concentrated nitric acid in the presence of silver nitrate to prevent volatilization of the chloride. In making a preliminary study of Van Slyke’s method before using it for a series...

1. Pericytes, which are contractile cells located on the outer wall of microvessels, are thought to be particularly important in the retina where the ratio of these cells to vascular endothelial cells is the highest of any tissue. Retinal pericytes are of interest since they may regulate capillary blood flow and because their selective loss is an early event in diabetic retinopathy, which is a ...

The effect of genotype and sex of Nigerian indigenous chickens (dwarf, Fulani ecotypes, neck, frizzle and normal feathered) on blood serum electrolytes and biochemical parameters were investigated using 40 chickens. The collected data were subjected to analysis via a 2 way ANOVA. The results revealed serum levels of sodium, potassium, chloride, uric acid, glucose, total protein, creatinin, albu...

In 1925, Holt, La Mer, and Chown (1) reported that the apparent solubility product [Ca++13[P04=J2 was greater in a solution of inorganic salts approximating the composition of serum than it was in solutions of sodium chloride of the same ionic strength. Very shortly thereafter, Sendroy and Hastings (2) recalculated values for pK’, Ca,(PO& from the data of Holt, La Mer, and Chown and also report...

HAVE INSTITUTED a colorimetric chloride procedure which has been in use for 3 years in our laboratory and has met with great success. This colorimetric method is based on a procedure used in automated syStems* (2, 3). It is extremely simple, quite accurate, and gives highly reproducible results even in the hands of student technicians. Those laboratories not having access to a chloridometer or ...

C-reactive protein (CRP) as it occurs in serum and in all but a very few pathological fluids is associated with a phosphorus-containing substance or substances of lipid character.' It can be obtained from the fraction of serum precipitable by 0.5 to 0.75 saturation with ammonium sulfate, following dialysis against dilute calcium chloride. The complex obtained by this procedure is insoluble in d...

CHLOROTHIAZIDE, commercially available as Diuril, was introduced to the general medical profession January 1, 1958. It had been available to clinical investigators during the previous year. In this span it has won wide acceptance as an oral diuretic and antihypertensive agent. These comments should be considered in the light of this relatively brief experience. The chemical structure of chlorot...