Urea is the principal nitrogenous waste product of metabolism and is generated from protein breakdown. It is eliminated from the body almost exclusively by the kidneys in urine, and measurement of its concentration, first in urine and later in blood, has had clinical application in the assessment of kidney (renal) function for well over 150 years. This is the first of two articles that together...

Carprofen or meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs), which may elicit a variety of renal disturbances. Prior to this study, the effects of carprofen or meloxicam on renal function in pigs were unknown. A total of 21 clinically healthy Goettingen miniature pigs (36.9 ± 7.22 kg) were divided into three groups based on what they were administered – carprofen, meloxicam or sali...

Received 2/18/2002; revised 3/4/2002; accepted 3/8/2002. For correspondence or reprints contact: Nan-Tsing Chiu, M.D., Department of Nuclear Medicine, National Cheng Kung University Hospital, 138 Sheng-Li Road, Tainan 704, Taiwan. Tel: (886)6-2353535 ext. 2480, Fax: (886)6-2766609, E mail: [email protected] Background: We conducted this study to explore the correlation of formula creatini...

Background: Microalbuminuria and serum creatinine are the specific markers of acute renal injury. Perinatal asphyxia is responsible for 50% of all neonatal deaths and nonoliguric acute renal injuryis one of its complications. This study was undertaken to determine the efficacy of serum creatinine and microalbuminuria for early diagnosis of renal injury in severely asphyxiated neonates in Calaba...

Key words: acute renal failure; interstitial nephritis; elevated serum total protein, together with a slight MHC class II antigen; tubular basement membrane decrease in serum albumin was noted. Serum creatinine immune deposition was 3.6 mg/dl and blood urea nitrogen was 53 mg/dl. Serum chloride was slightly increased (112 mmol/l). The endogenous creatinine clearance was 21.6 ml/min/ 1.73 m2. Se...

INTRODUCTION Diabetic nephropathy is the most prevalent cause of end-stage renal disease. Besides factors such as angiotensin II, cytokines, and vascular endothelial growth factor, uric acid may play a role as the underlying cause of diabetic nephropathy. We evaluated allopurinol effects on proteinuria in diabetic patients with nephropathy. MATERIALS AND METHODS In a double-blinded randomized...

Background: Iran is one of the major consumers of opium and opiate substances in the world. Addiction has become a very important issue in the 21st century and an urgent one in Iran. The consumption of this substance leaves a variety of impacts on the human body. The goal of this study is to investigate the changes of the biochemical parameters derived from opiate substances in addicts during t...

the aim of this study was to evaluate the effects of balancing low protein diets for methionine and lysine on performance of early lactation holstein cows under hot environmental temperature. twenty one multiparous holstein cows in early lactation were allocated to three experimental rations including, 1) high protein ration with 17.5% cp, 2) medium protein ration with 16% cp and 12 g/d rumen p...

The Beckman Astra-8 is a computerized, discrete-microsample, multiple-test clinical chemistry analyzer. We have examined its capability to measure urine Na+, K+, Cl-, urea nitrogen, glucose, and creatinine and found that (a) the Astra measurements are linear, accurate, and precise in concentration ranges of urine analytes; (b) urine analyte concentrations measured with the Astra correlate well ...

BACKGROUND AND OBJECTIVES The objective of this study was to describe the normal range of serum cystatin C and identify factors associated with variability in serum cystatin C contrasting with factors that are known to influence creatinine levels in the general US adolescent population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Serum cystatin C and creatinine were measured in 719 particip...