Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...

The survival of patients with thalassemia major has progressively improved with advances in therapy; however, osteoporosis remains a frequent, unresolved issue [1]. Adequate circulating levels of vitamin D are essential for optimal skeletal health and reducing fracture risk [2]. Vitamin D insufficiency is reported in the majority of patients with thalassemia in the USA [3] and elsewhere [4–10],...

Introduction: Compared with the general population, hemodialysis patients are at increased risk of vascular calcification, which in turn is associated with an increased risk of mortality. Regarding the role of vitamin D in bone formation, regulation of calcium, phosphate and iPTH level and correlation of these variables in survival, this study was performed to evaluate the vitamin D serum level...

Although 1,25-dihydroxyvitamin D [1,25(OH)2D] is the biologically active form of vitamin D, measurement of the total serum 25-hydroxyvitamin D [25(OH)D] level is the gold standard used to define vitamin D status. Currently, it is widely accepted that serum 25 (OH) D levels below 20 ng/ml defines vitamin D deficiency. According to this definition, there appears to be pandemic vitamin D deficienc...

background: in recent years, epidemiologic and laboratory studies have implied that vitamin d deficiency has a role in the pathogenesis of breast cancer. it has shown that vitamin d can prevent tumor progression induced by carcinogens and inhibit the carcinogenic effects of high fat diet on breast tissue and growth of tumor cells. this study aimed to evaluate serum 25-hydroxyvitamin d level and...

Introduction: Pregnancy poisoning or preeclampsia is a serious and specific disorder of pregnancy that affects 8% of the pregnant women. Similar studies conducted in this regard showed disagreements about the association between the vitamin D deficiency and preeclampsia. Hence, due to different results and limited sشtudies in this area, the present study was conducted to evaluate the serum leve...

results there were no significant differences in baseline characteristics between two groups except serum ast level. complete evr rate at week 12 in the vitamin d group was significantly higher than the controls (100% vs 84.4%; p = 0.023) whereas this figure was not significant when genotypes 1 and 4 or 2 and 3 in the test group were compared to those of the control (100% vs 86.7%; p = 0.19 and...

maternal vitamin d deficiency is one of the major risk factors for neonatal vitamin d deficiency followed by neonatal hypocalcaemia. the aim of this study is to determine the relationship between delayed neonatal hypocalcaemia and maternal vitamin d deficiency. this is a descriptive cross-sectional study. target population of this study included all term and preterm neonates with delayed hypoca...