Owing to its subjective nature, behavioral pure-tone audiometry often is an unreliable testing method in uncooperative subjects, and assessing the true hearing threshold becomes difficult. In such cases, objective tests are used for hearing-threshold determination (i.e., auditory brainstem evoked potentials [ABEP] and frequency-specific auditory evoked potentials: slow negative response at 10 m...

Sensorineural hearing loss (SNHL) is a common adverse effect for nasopharyngeal carcinoma (NPC) patients treated with chemoradiotherapy. We report a case of 12-year follow-up from a patient with stage IIB NPC, treated in 2004 with intensity-modulated radiotherapy and cisplatin-based chemotherapy. Pure-tone audiograms were conducted before treatment and at two other points in the 12-year period ...

Mutations in the ATP6V1B1 and ATP6V0A4 genes, encoding subunits B1 and 4 of apical H(+) ATPase, cause recessive forms of distal renal tubular acidosis (dRTA). ATP6V1B mutations have been associated with early sensorineural hearing loss (SNHL), whereas ATP6V0A4 mutations are classically associated with either late-onset SNHL or normal hearing. The phenotype and genotype of 39 new kindreds with r...

This review deals with the characteristics of various inflammatory mediators identified in the middle ear during otitis media and in cholesteatoma. The role of each inflammatory mediator in the pathogenesis of otitis media and cholesteatoma has been discussed. Further, the relation of each inflammatory mediator to the pathophysiology of the middle and inner ear along with its mechanisms of path...

Dire consequences can occur after any medical or surgical procedure. Certain procedures may even cause sensorineural hearing loss (SNHL). Previous studies have demonstrated that certain surgical and medical procedures may result in hearing losses of varying degrees. Although hearing loss is a well-known phenomenon, little consistent information exists about hearing loss after medical or surgica...

As a group, adults with bilateral symmetric sensorineural hearing loss (SNHL) who receive a monaural hearing aid fitting experience a progressive decline in their word recognition score (WRS) for monosyllabic word materials in the unaided ear but not in the aided ear. However, adults with binaural fittings do not demonstrate a similar deterioration in their WRS. In an effort to determine the ro...

The etiology of sensorineural hearing loss (SNHL) in children may be viral. This cross-sectional study aimed to determine the role of viral infectious agents in children with idiopathic SNHL. Of 119 children with SNHL aged 3-168 months undergoing cochlear implant surgery at a hospital in Tehran, no cause could be established in 18 cases (15.1%). Cytomegalovirus (CMV) and herpes simplex virus (H...

BACKGROUND AND PURPOSE Sensorineural hearing loss (SNHL) is a rare complication of stapes surgery that may arise for many reasons. Usually, the pathogenesis of SNHL can be established by clinical and CT examinations. The purpose of this study was to evaluate the utility of MR imaging when CT findings are normal or not contributive. METHODS Eleven patients with SNHL (in some instances, associa...

Introduction: The aim of this study was to evaluate the width bony cochlear nerve canal (BCNC) in children with congenital sensorineural hearing loss (SNHL) and "normal" findings on thin section temporal bone CT. Material methods: BCNC retrospectively evaluated two groups patients. group included 11 (22 canals) aged 2-12 years, congenital, bilateral SNHL who underwent implantation (CI) from Jul...