spermatozoa generate reactive oxygen species (ros) in physiological amounts which play a role in sperm functions during sperm capacitation acrosome reaction (ar) and oocyte fusion. in addition damaged sperm are likely to be the source of ros. the most important ros produced by human sperm are hydrogen peroxide superoxide anion and hydroxyl radicals. besides human seminal plasma and sperm posses...

objective(s) bone is a dynamic tissue that is continuously renewed throughout life by the process of bone remodeling. antioxidant system might be involved in the pathogenesis of bone loss, so the aim of this study was to evaluate the total antioxidant capacity (tac), vitamin c and vitamin e levels of plasma besides measuring enzymatic antioxidants, superoxide dismutase (sod), catalase (cat) and...

Experiments have been reported in Paper I (1) in which the proteins of bovine seminal plasma were subjected to preliminary and electrophoretic characterization. In order to characterize this protein system further, ultracentrifugal and immunological methods have been applied. A limited amount of work has been reported on the ultracentrifugation of the seminal plasma proteins. Ross (2) has noted...

BACKGROUND Total antioxidant capacity (TAC) provides an assessment of antioxidant activity and synergistic interactions of redox molecules in foods and plasma. OBJECTIVE We investigated the validity and reproducibility of food-frequency questionnaire (FFQ)-based TAC estimates assessed by oxygen radical absorbance capacity (ORAC), total radical-trapping antioxidant parameters (TRAP), and ferri...

Inositol (me8oinositol or myoinositol) occurs very widely in plants, animals and micro-organisms (Fleury & Balatre, 1947; Courtois, 1951; Hawthorne & Chargaff, 1954; Mann, 1954a). It occurs in the free state as well as in the form of inositol phosphatides, while in plants it is often present as the hexaphosphate, phytic acid. Treatment of liver and nervous tissue by the standard procedure of Sc...

Trans-generational transfer of non-genetic, maternal resources such as hormones can have a substantial influence on offspring phenotype in many vertebrate species. In birds, maternal androgens enhance both growth and competitive behaviour, but also suppress the immune system. It has been hypothesised that high levels of egg androgens could also influence the prooxidant-antioxidant balance throu...

BACKGROUND Serum selenium concentrations and the activity of plasma glutathione peroxidase (GPx) decrease with the progression of chronic kidney disease (CKD) in human patients. Selenium is considered a limiting factor for plasma GPx synthesis. Plasma total antioxidant capacity (TAC) is decreased in CKD cats in comparison to healthy cats. HYPOTHESIS Serum selenium concentrations and plasma an...

Abnormal reactive oxygen species (ROS) production is associated with defective sperm function. Superoxide dismutase (SOD) is related with the scavenging of seminal ROS. We aimed to determine the effect of SOD activities of spermatozoa and seminal plasma on sperm quality. Semen samples from infertile couples who consented to the analyses were divided into two groups: 1) normospermia (n = 20); an...

Objective: To observe the clinical efficacy and safety of low dose tacrolimus (TAC) combined with tripterygium (TW) in treatment of steroid resistant nephritic syndrome (SRNS). Method: The patients, who were diagnosed with mesangial proliferative glomerulonephritis (MesPGN) and focal segmental glomerulosclerosis (FSGS) by biopsy and failed to respond to a 3-month treatment with prednisone (1 mg...