Efavirenz is a drug with an absorption window. Its oral bioavailability is 40-50%. The aim of this work was to formulate solid self-emulsifying drug delivery system to improve the solubility and bioavailability of efavirenz. Solubility of Efavirenz was determined in various vehicles like oils, surfactants and co surfactants. Which, upon dilution with aqueous media, spontaneously form fine oil i...

Previous research has shown that people reporting contact with aliens, known as "experiencers", appear to have a different psychological profile compared to control participants. They show higher levels of dissociativity, absorption, paranormal belief and experience, and possibly fantasy proneness. They also appear to show greater susceptibility to false memories as assessed using the Deese/Roe...

The nature of the water vapour continuum has been great scientific interest for more than 60 years. Here, self-continuum absorption spectra are retrieved at temperatures 398 K and 431 pressures from 1000 to 4155 mbar in 8800 10,600 cm−1 bands using high-resolution FTS measurements. For observed conditions, MT_CKD-3.2 model underestimates on average by 1.5–2 times. We use hypothesis that dimers ...

Low-energy X and γ radiations (for example of 210Pb: Eγ = 46.5 keV) are effectively self-absorbed even in thin environmental samples, including air filters with captured dust or contaminated soil, as well as in bottom sediment matrixes with limited quantities of the samples. In this paper, a simple method for the direct analysis of 210Pb (T1/2 = 22.3 years) by gamma-ray spectrometry in environm...

We consider the slow nonlinear diffusion equation subject to a strong absorption rate and construct local self-similar solutions for reversing (and anti-reversing) interfaces, where an initially advancing (receding) interface gives way to a receding (advancing) one. We use an approach based on invariant manifolds, which allows us to determine the required asymptotic behaviour for small and larg...

Exciton optical absorption in self-similar aperiodic one-dimensional systems is considered, focusing our attention on Thue-Morse and Fibonacci lattices as canonical examples. The absorption line shape is evaluated by solving the microscopic equations of motion of the Frenkel-exciton problem on the lattice, in which on-site energies take on two values, according to the Thue-Morse or Fibonacci se...

We implemented a self-consistent, real-space x-ray absorption calculation within the FDMNES code. We performed the self-consistency within several schemes and identified which one is the most appropriate. We show a method that allows a rigorous setting of the Fermi level and thus an estimation of the energy cutoff for the identification and elimination of the occupied states. We investigated wh...

Self absorption is a significant source of error in the assay of Pu-bearing waste by gamma-ray spectrometry. Differential absorption of the 129keV and 414keV lines can be used as a means of determining self-absorption and applying a correction. With a view to refining this technique, the behaviour of the 129keV and 414keV lines from Pu as they emerge from lumps of Pu has been studied using a po...