OBJECTIVES A breakthrough seizure is one occurring after at least 12 months seizure freedom while on treatment. The Driver and Vehicle Licensing Agency (DVLA) allows an individual to return to driving once they have been seizure free for 12 months following a breakthrough seizure. This is based on the assumption that the risk of a further seizure in the next 12 months has dropped <20%. This ana...

PURPOSE To investigate the factors, including those associated with ictal scalp EEG results, related to surgical outcome in patients with pathologically proven mesial temporal sclerosis. METHODS We studied 51 consecutive patients who underwent anterior temporal lobectomy and had at least 4 years of follow-up. Surgical outcome was classified as being seizure-free or not seizure-free during the...

Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons. It has also been shown to acutely induce epileptic seizure behavior in freely moving rats. However, whether CTZ induced seizure rats could develop to have recurrent seizure still remains unknown...

INTRODUCTION Clinical and outcome profiles of childhood seizures can be different in resource limited settings where neurologists face lots of challenges in diagnosis and management of seizure. This study was conducted to investigate the clinical profile, causes and outcome of afebrile seizures in children in resource limited settings. METHODS This was a prospective hospital based study. Chil...

Seizures were monitored using both cuff method and EEG, during the first ECT session in 158 consecutive patients. All developed adequate EEG seizures (≥25 seconds). Twelve patients (8%) did not develop adequate motor seizures (15 seconds), of whom ten had no convulsive response. EEG seizure duration was less than 120 seconds in 117 patients (Group-A) and 120 or more seconds (prolonged) in the r...

objective studies on the effect of various antiepileptic drugs on serum lipids show contradictory results. we aimed to find the effect of phenobarbital and sodium valproate monotherapy on serum lipid profile and liver function tests in epileptic children. materials & methods this cohort study was conducted in amirkola children hospital. one hundred and ten children with epilepsy were included i...

objective febrile seizure is the most common seizure disorder in children. its pathophysiology is not fully understood yet; however, some risk factors have been cited for it. iron is one of these influential elements and is involved in the metabolism of some neurotransmitters which are reduced in irondeficiency anemia and also increases the sensitivity of neural cells during a febrile episode. ...

how to cite this article: heydarian f, rezaeian a. relationship between changes in serum sodium level and seizures occurrence in children with hypernatremic dehydration. iran j child neurol. 2013 autumn;7(4): 35- 40.   objective to assess any relationship between serum sodium changes and seizure occurrence in children aged 2 months to 5 years with hypernatremic dehydration.   materials & method...

results the mean ± sd of the clonic seizure threshold was 61.84 ± 8.53 in the group that received estradiol, while it was 71.70 ± 10.85 in the control group, 64.69 ± 3.23 in rats with laparotomy without removing the ovaries, 51.30 ± 6.84 in rats with laparotomy and removing the ovaries, 52.7 ± 7.18 in ovariectomized rats that received sesame oil as vehicle, and 59.2 ± 4.91, in the soy groups. t...