The effects of a mild freeze injury to the skin on responses of nociceptive dorsal horn neurons to cold and heat stimuli were examined in anesthetized rats. Electrophysiological recordings were obtained from 72 nociceptive spinal neurons located in the superficial and deep dorsal horn. All neurons had receptive fields (RFs) on the glabrous skin of the hindpaw, and neurons were functionally divi...

The life stages of seed germination and seedling establishment play a vital role in maintaining plant populations and determining range dynamics of species. Thus, it is not surprising that specific germination requirements and dormancy mechanisms have evolved in all major angiosperm clades. In a rapidly changing climate, we face growing pressure to manage, conserve and restore native plant spec...

Ischemia/reperfusion injury associated with kidney transplantation induces profound acute injury, influences early graft function, and affects long-term graft outcomes. To determine whether renal dendritic cells play any role during initial innate ischemia/reperfusion injury and the subsequent development of adaptive immune responses, we studied the behavior and function of renal graft and host...

Trauma-induced cold intolerance (cold sensitivity) is characterised by pain, stiffness, altered sensibility, or colour change associated with cold exposure (Campbell and Kay 1998), and is common after nerve injury or surgery (Irwin et al 1997). The Immersion in Cold water Evaluation (ICE) is a cold stress test administered through a standardised protocol where the hand is immersed in cold water...

Seedlings from two families of the BC3F3 backcross generation of the American chestnut (Castanea dentata) and Chinese chestnut (C. mollissima) were cultured in 2013 in Missouri using the Root Production Method®, a container-based system used to avoid disease problems associated with bareroot nursery production. After culling part of the seedlings at initial leaf formation in a greenhouse, both ...

Recent evidence exists that enoxaparin can reduce brain injury because of its anticoagulant activity. To investigate the potential therapeutic effect of enoxaparin on cold-induced traumatic brain injury, at 20 minutes after modeling, male BALB/c mouse models of cold-induced traumatic brain injury were intraperitoneally administered 3 and 10 mg/kg enoxaparin or isotonic saline solution. Twenty-f...

BACKGROUND Pain is elicited by cold, and a major feature of many neuropathic pain states is that normally innocuous cool stimuli begin to produce pain (cold allodynia). To expand our understanding of cold induced pain states we have studied cold pain behaviors over a range of temperatures in several animal models of chronic pain. RESULTS We demonstrate that a Peltier-cooled cold plate with +/...

Pythium species are the most common seedling disease pathogens isolated from rice in producers’ fields in Arkansas. These studies examined the value of Pythium resistance in breeding lines with cold tolerance in early-season planting environments. These lines show promise for reliable stand establishment in Arkansas. The breeding line RU0701124 had more plants/acre and greater relative root wei...

Unlike other animals that live outside the tropics, humans are susceptible to peripheral cold injuries. The highest homeostatic priority is to maintain the body’s core temperature. This is accomplished through peripheral vasoconstriction and shunting, which prevent adequate heat distribution to the extremities. As a result, failure to achieve adequate protection from the environment results in ...

Most insects have the ability to alter their cold tolerance in response to temporal temperature fluctuations, and recent studies have shown that insect cold tolerance is closely tied to the ability to maintain transmembrane ion gradients that are important for the maintenance of cell membrane potential (Vm). Several studies have therefore suggested a link between preservation of Vm and cellular...