BACKGROUND Although glaucoma is a leading cause of blindness worldwide, yet there are no large databases where risk factors, current management options and outcomes may be evaluated. With this concept in mind, Dallas Glaucoma Registry was established to focus on an ethnically mixed North Texas population. METHODS This is a retrospective, chart review of 2,484 patients (4,839 eyes) with glauco...

Purpose To compare the levels of autotaxin (ATX), lysophosphatidic acid (LPA), and lysophosphatidylcholine (LPC) in the aqueous humor (AH) of healthy control subjects with those of patients with different subtypes of glaucoma, and also to investigate the relationship of the ATX-LPA pathway with IOP and subtype of glaucoma. Methods This study included 164 eyes of 164 consecutive cases of catar...

We report a patient with traumatic glaucoma with features of unilateral pigment dispersion. This rare form of secondary glaucoma has only been reported twice previously, with both patients demonstrating angle recession, indicating associated damage to the trabecular meshwork. To our knowledge, this is the first such case reported in which angle recession was absent.

We report a case of intractable glaucoma following an uncomplicated secondary posterior capsulotomy in a 48-year-old male with Fuchs's heterochromic cyclitis. The patient had been free of inflammation and glaucoma since cataract extraction 27 years previously. We also report the results of phenotypic analysis of lymphocytes removed from the anterior chamber.

Introduction: Ghost cell glaucoma (GCG) is a very rare secondary open angle glaucoma, in which there sustained increase intraocular pressure (IOP) due to obstruction of the trabecular meshwork (TM) passage ghost cells (GC) from vitreous into anterior chamber, after hemorrhage (VH). Clinical Case: We present case male patient with history and IOP elevation right eye (RE). Medical treatment was i...

Neovascular glaucoma is caused by tissue hypoxia, especially secondary to posterior segment diseases. Angiogenic factors precipitate neovascularization in trabecular meshwork. Due to this, aqueus outflow is obtructed and intraocular pressure is increased. The most common reasons of neovascular glaucoma are diabetic retinopathy, central retinal vein occlusion and ocular ischemic syndrome. Anothe...

PURPOSE Glutathione S-transferases (GSTs) are a family of enzymes that inactivate xenobiotics and endogenous end products formed as secondary metabolites during oxidative stress. In humans, GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) are associated with a variety of pathologic processes including certain ophthalmologic diseases. METHODS We compared the prevalence of GSTT1 and GS...

Our objective is to investigate which factors and patient characteristics are associated with success in Trabectome surgery.A total of 658 phakic cases with at least of 12 months follow-up were included in the analysis. Baseline demographics and medical data were collected. The main outcome measure was intraocular pressure (IOP), glaucoma medication (Rx), and secondary glaucoma surgery if any. ...

to compare the success of patients with ocular hypertension, secondary to pars plana vitrectomy and silicon oil tamponade, who had an ex-press glaucoma filtration device p50 (alcon laboratories, inc. fort worth, texas, usa) to those who had conventional trabeculectomy this study has been performed. the records of 10 eyes of 10 consecutive subjects who had ex-press implants and 9 eyes of 9 conse...