b a ckground: the management of internal mammary (im) nodes in breast cancer lacks a well-defined consensus. lymphoscintigraphy identifies up to one-third of breast cancer patients with extra-axillary drainage, which is mainly located in the im chain. our aim in this meta-analysis is to identify the lymphoscintigraphy technique variables that effect im node identification. m ethods: an internet...

The theory on multi-echelon production/inventory systems is a core theory within supply chain management. It provides useful insights for design of supply chains and may be used for tactical and operational planning decisions. The multi-echelon theory started with the seminal paper of Clark and Scarf in 1960. In this tutorial, we describe for which systems optimal policies are known, which key ...

C often face nonstationary demand due to product life cycles and seasonality, and nonstationary demand complicates supply chain managers’ inventory decisions. This paper proposes a simple heuristic for determining stocking levels in a serial inventory system. Unlike the exact optimization algorithm, the heuristic generates a near-optimal solution by solving a series of independent single-stage ...

We consider customer response time minimization in a two-echelon supply chain system with stochastic demand where the first echelon consists of one production plant and the other of one retailer. Traditionally models of this type only seek to minimize traditional operating costs. However, because of the highly competitive nature of the market, it is also essential for the manufacturer to respon...

A stream is a continuous version of a supply chain. It is like a series inventory system, but stock can be held at any point along a continuum, not just at discrete stages. We assume stationary parameters and aim to minimize the long-run average total cost. We show that a stationary continuous-stage echelon base-stock policy is optimal. That is, at each geographic point along the supply stream,...

Improved walking comfort has been linked with better bio-mimicking of the prosthetic ankle. This study investigated if a hydraulic ankle/foot can provide enough motion in both the sagittal and frontal planes during level and camber walking and if the hydraulic ankle/foot better mimics the biological ankle moment pattern compared with a fixed ankle/foot device. Five active male unilateral trans-...

We consider an M/G/∞ exchangeable-item repair system with spares and ample servers to which arriving customers bring groups of random size B identical items for repair. An exact formula for the waiting time distribution and a computationally efficient approximation are presented for this system. From this, we not only have the standard fillrate, but a practical extension of this concept to a 'f...

Managing income is a considerable dimension in supply chain management in current economic atmosphere. Real world situation makes it inevitable not to design or redesign supply chain. Redesign will take place as costs increase or new services for customers’ new demands should be provided. Pricing is an important fragment of Supply chain due to two reasons: first, represents revenue based ...

Differentiated thyroid cancers may be associated with regional lymph node metastases in 20-50% of cases. The central compartment (VIupper VII levels) is considered to be the first echelon of nodal metastases in all differentiated thyroid carcinomas. The indication for central neck dissection is still debated especially in patients with cN0 disease. For some authors, central neck dissection is r...

Our incentive is to study the behaviour of lot-sizing rules in a multilevel context when forecast demand is subject to changes within the forecast window. To our knowledge, only Bookbinder and Heath (1988) proposed a lot-sizing study in a multi-echelon rolling schedule with probabilistic demands. But their simulation study was limited to two arborescent structures with 6 nodes. By means of an e...