Modular chiral dendrimers with monodentate phosphoramidite ligands located at the core were synthesized and applied in the Rh-catalyzed asymmetric hydrogenations, afforded unprecedented enhancement of enantioselectivity.

The overall cost of companies dealing with the distribution tasks is considerably affected by the way that distributing vehicles are procured. In this paper, a more practical version of capacitated vehicle routing problem (CVRP) in which the decision of purchase or hire of vehicles is simultaneously considered is investigated. In CVRP model capacitated vehicles start from a single depot simulta...

Berhane Beyene Mentaye*, Mebratu Zelalem, Angelo Asha, Yosef Tiruneh, Aklog Afework, Menberu Tedela, Tsion Bezuneh, AlmazG/senbet, Femi Oyewole, Almaz Abebe, Tilahun Woldemichael and Oyewale Tomori Polio Laboratory and Virology and Ricketisiology Team, Ethiopian Health and Nutrition Research Institute, Disease Prevention and Control Department, Ministry of Health of Ethiopia, World Health Organ...

MARVIN REID,1,2 ASHA BADALOO,2 TERRENCE FORRESTER,2 JOHN F. MORLESE,1,2 MARGARET FRAZER,1 WILLIAM C. HEIRD,1 AND FAROOK JAHOOR1 1United States Department of Agriculture/Agricultural Research Service, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030; and 2Tropical Metabolism Research Unit, University of the West Indies, Mona, Kingst...

The inclusion complexes of a new family of nonionic amphiphilic calix[4]arenes with the anti-inflammatory hydrophobic drugs naproxen (NAP) and ibuprofen (IBP) were investigated. The effects of the alkyl chain's length and the inner core of calix[4]arenes on the interaction of the two drugs with the calix[4]arenes were explored. The inclusion complexes of Amphiphiles 1a-c with NAP and IBP increa...

In this paper we present a new approach to tackle complex routing problems with an improved state representation that utilizes the model complexity better than previous methods. We enable by training from temporal differences. Specifically Q-Learning is employed. show our achieves state-of-the-art performance for autoregressive policies sequentially insert nodes construct solutions on Capacitat...

Due to the suddenness and uncertainty of COVID-19, sufficient emergency resources should be allocated appropriate space within a limited time. In order ensure smooth implementation resource scheduling, must timely effectively supplied. Therefore, it is great significance study how reasonably distribute optimize vehicle routing problem improve efficiency emergency. Based on research capacitated ...

objective status epilepticus (se) has been described as a series of major motor seizure without recovery of consciousness between seizures. se is a medical emergency that requires prompt diagnosis and appropriate treatment. in this article we shall conclude history, epidemiology, etiology, risk factors, the best management as well as the prognosis of the condition.