Schistosomiasis and soil-transmitted helminthiasis (STH) are the most common types of parasitic infections in the world. These diseases have major health and socio-economic repercussions, and constitute an important public health problem in developing countries. Human schistosomiasis is caused by six species of schistosomes, i.e. Schistosoma haematobium, Schistosoma mansoni, Schistosoma japonic...

Serpins are a structurally conserved family of macromolecular inhibitors found in numerous biological systems. The completion and annotation of the genomes of Schistosoma mansoni and Schistosoma japonicum has enabled the identification by phylogenetic analysis of two major serpin clades. S. mansoni shows a greater multiplicity of serpin genes, perhaps reflecting adaptation to infection of a hum...

Sumary The identification of a escrotal mass without pain or report of trauma should be investigated to rule out scrotal cancer. We report the case of a young Brazilian boy who underwent orchiectomy after magnetic resonance imaging (MRI) and duplex scan (DS) indicating a high possibility of cancer. Blood exams ruled out the possibility of cancer. Testicular biopsy was not indicated. After surge...

Background Schistosomiasis remains a severe problem of public health in developing countries [1]. Several reports show that praziquantel, the drug of choice for treating schistosomiasis, can select Schistosoma mansoni strains resistant to the drug. Thus, developing new drugs against this parasitosis is a highly desirable goal [2]. In this context, enzymes involved in energetic metabolism could ...

Schistosoma are trematode blood flukes of the family Schistosomidae affecting the urinary and gastro-intestinal tracts. Riverine areas of the world such as in Africa, Eastern Mediterranean, Central American and East Asia are endemic for the disease, with S. haematobium accounting for most of the symptomatic genital infection. A case of a 25-year-old woman with 8 weeks amenorrhoea, lower abdomin...

In our study, in a 52-year-old man, specific and nonspecific findings of Schistosoma infestation were examined using ultrasonography, computed tomography, and magnetic resonance imaging. On computed tomography, capsular and septal calcifications and contrast enhancement of the liver capsule were seen. On T1-weighted magnetic resonance images diffuse hypointensity was seen in periportal spaces; ...