OBJECTIVES Small animal imaging has recently been focused on basic nuclear medicine. We have designed and built a small animal SPECT imaging system using a semiconductor camera and a newly designed collimator. We assess the performance of this system for small object imaging. METHODS We employed an MGC 1500 (Acrorad Co.) camera including a CdTe semiconductor. The pixel size was 1.4 mm/pixel. ...

Image analysis in the presence of surface scatter due to residual optical fabrication errors is often perceived to be complicated, nonintuitive, and achieved only by computationally intensive nonsequential ray tracing with commercial optical analysis codes such as ASAP, Zemax, Code V, TracePro, or FRED. However, we show that surface scatter can be treated very similarly to conventional wavefron...

Accurate scatter correction is one of the major problems facing quantitative 3D PET and many methods have been developed for the purpose of reducing the resultant degradation of image contrast and loss of quantitative accuracy. A new scatter correction method called Statistical Reconstruction-Based Scatter Correction (SRBSC) is proposed in this paper and evaluated using Monte Carlo simulations,...

To optimize cell separations by centrifugal elutriation, we constructed an on-line computer-controlled multiparametric light-scatter system. A bypass sample flow, at the outlet of an elutriation rotor, is hydrofocussed and three scatter parameters of each cell are determined up to a maximum of 15,000 cells/second. The 18-bit representation of the parameter values are cumulatively stored by mean...

A class of projection based scatter depth functions is introduced and studied. In order to use the depth function effectively, some favorable properties are suggested for the common scatter depth functions. We show the proposed scatter depth totally satisfies these desirable properties and its sample version possess strong and √ n uniform consistency. Under some regularity conditions, the limit...

It is shown that any pair of scatter and spatial scatter matrices yields an estimator of the separating matrix for complex-valued independent component analysis (ICA). Scatter (resp. spatial scatter) matrix is a generalized covariance matrix in the sense that it is a positive definite hermitian matrix functional that satisfies the same affine (resp. unitary) equivariance property as does the co...

The purpose of this study was to evaluate different approaches for scatter artifact reduction in the field of dimensional computed tomography (CT). The methods we investigated can be subdivided into one software-based method and three hardware-based methods. The software-based method uses a Monte Carlo scatter simulation to estimate scatter intensities for an initial model of the geometrical an...

We describe an ordinary Poisson list-mode expectation maximization (OP-LMEM) algorithm with a sinogram-based scatter correction method based on the single scatter simulation (SSS) technique and a random correction method based on the variance-reduced delayed-coincidence technique. We also describe a practical approximate scatter and random-estimation approach for dynamic PET studies based on a ...