Scabies is an infectious skin disease caused by the human-specific ectoparasite Sarcoptes scabiei var. hominis. Despite comprehensive study of scabies, problem its timely diagnosis in low-mobility patients with neurological and cognitive impairments remains relevant all over world. Simultaneous administration a large number medications to limited mobility may mask clinical manifestations scabie...

No commercial immunodiagnostic tests for human scabies are currently available, and existing animal tests are not sufficiently sensitive. The recombinant Sarcoptes scabiei apolipoprotein antigen Sar s 14.3 is a promising immunodiagnostic, eliciting high levels of IgE and IgG in infected people. Limited data are available regarding the temporal development of antibodies to Sar s 14.3, an issue o...

Molecular studies on scabies, a disease of considerable human and veterinary significance, have been limited because of the difficulty of obtaining the causative organism Sarcoptes scabiei, the "itch mite." We have used skin from the bedding of crusted scabies patients as a source of mites for the construction of libraries of cDNAs from S. scabiei var. hominis in the bacteriophage lambda vector...

Scabies is an important public health problem in residential care homes. Delayed diagnosis contributes to outbreaks, which may be prolonged and difficult to control. We investigated factors influencing outbreak recognition, diagnosis and treatment, and staff experiences of outbreak control, identifying areas for intervention. We carried out a semi-structured survey of managers, affected residen...

Introduction Reports of Norwegian or crusted scabies occurring in England are rare (Calnan, 1950). In this condition itching is not a constant symptom, burrows may not be present and the acarus may be found on the head and neck. The acarus is seen within scales and the gross hyperkeratosis may give the skin the appearance of the bark of a tree. Norwegian scabies has been reported in mental defe...

Background: Scabies, a contagious skin infestation by the mite Sarcoptes scabieii. It has no gender differences and infects all age group. This disease affects more than 300 million people per year worldwide, resulting in considerable morbidity, especially resource-limited countries. Aims Objectives: To find out prevalence risk factor of scabies rural population to recommend measures for preven...

BACKGROUND Although senile dementia patients in long-term care facilities are at leading risk of scabies, the epidemiologic characteristics of this disease have yet to be fully clarified. This study documents the findings of a ward-scale nosocomial outbreak in western Japan from 1989-90, for which permission to publish was only recently obtained. METHODS A retrospective epidemiologic study wa...

BACKGROUND Scabies is one of the commonest dermatological conditions globally; however it is a largely underexplored and truly neglected infectious disease. Foremost, improvement in the management of this public health burden is imperative. Current treatments with topical agents and/or oral ivermectin (IVM) are insufficient and drug resistance is emerging. Moxidectin (MOX), with more advantageo...

A biological model of scabies infection dynamics and treatment explains why mass drug administration does not lead to elimination. Abstract Despite a low global prevalence, infections with Sarcoptes scabiei, or scabies, are still common in remote communities such as in northern Australia and the Solomon Islands. Mass drug administration (MDA) has been utilised in these communities, and although...