The copper-catalyzed tandem oxidative cyclization of cinnamamides with benzyl hydrocarbons through the direct cross-dehydrogenative coupling of sp(3) and sp(2) C-H bonds has been developed. Satisfactorily, ethers, alcohols and alkanes could also be used instead of benzyl hydrocarbons in this transformation, which allows rapid access to diverse dihydroquinolinones in one step.

This report consists of an evaluation of a commercially available photoelectric clot timer which can be used for performing prothrombin times. In the last two years, approximately 40,000 determinations have been satisfactorily performed with this apparatus. In addition, with the use of the timer, we have been able to pick up unsuspected fibrinogen deficiencies during the course of the performan...

Haemodynamic changes (supraventricular tachycardia, decreases in arterial pressure) were observed during laryngoscopy and intubation of the trachea in a patient receiving nifedipine and verapamil. Before the induced stresses of laryngoscopy and tracheal intubation, these drugs had controlled the patient's arterial pressure and heart rate satisfactorily, and possible reasons why this was not so ...

A silica gel medium was developed for the enumeration of petroleumlytic microorganisms in the marine environment. The medium was satisfactorily used for the investigation of the vertical distribution of bacteria in seawater from the surface to 1,000 m depth of western north Pacific central water as well as the neritic region of Japan.

Concentration of polyethylene glycol (PEG) has been measured satisfactorily using only 0.25 ml of intestinal aspirate (containing approximately 2.5 mg/l PEG). Hyden's turbidimetric assay was modified by reading turbidity at 420 mmu. The addition of extra protein was found to facilitate filtration after protein precipitation.

After comparing our previous and newer results for numerous oxidative aromatic iodination experiments using various brands of active MnO2 as the oxidants,we recommend the use of a Chemical Manganese Dioxide (Aldrich CMD; 90 +% MnO2) as the oxidant of choice, since it is satisfactorily pure and chemically active, and is notably less costly than other options.

The problems of cardio-vascular surgery in infancy cannot be satisfactorily included in this short review, which will deal with thoracic diseases other than those of the heart and great vessels. The problems will be considered under five headings:I. Oesophageal atresia and stenosis. 2. Diaphragmatic hernia. 3. Mediastinal cysts and neoplasms. 4. Lung cysts and infections. 5. Deformities of the ...

The Windermere humic aqueous model (WHAM) initially designed to model metal cation binding on humic substances were applied in predictive ecotoxicology [2]. For terrestrial higher plants, a recent investigation showed that WHAM was able to satisfactorily model cadmium (Cd), nickel (Ni), and zinc (Zn) concentrations in pea (Pisum sativum L.) roots, but that it overestimated the Cu concentration ...

Arguments over the definition of obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have still not been satisfactorily resolved. As a result, robust estimates of the prevalence of OSAHS are not possible. New approaches are needed to identify those who have "CPAP responsive" disease, enabling more accurate estimates to be made of the prevalence of the sleep apnoea syndrome in the community.

Previous developments on zero-thickness interface elements for coupled HydroMechanics problems are briefly described, followed by some new geomechanical applications, particularly to hydraulic fracture in rock. The results are compared satisfactorily to approximate formulas and previously published numerical results. Once verified, the model is applied to new cases to show the capabilities of t...